Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.

Abstract: An apparatus and method for embedding particles into the polymer matrix of a medical device are disclosed. The apparatus may include an electrostatic spray nozzle adapted to direct a stream of nanoparticles dissolved in a solution toward a positive outlet. A medical device, mounted onto an electrode, can then be placed into or proximate the stream such that upon energization of the electrode, the charged particles are redirected from the outlet toward the electrode. By spacing the electrode and energizing the electrode appropriately, the charged particles can be accelerated to a degree sufficient to cause the charged particles to embed themselves into the polymer matrix of the medical device.