Abstract: A novel surface treatment is provided for portions of filter media coming in contact with the filter media holder, such as filter housing. In certain applications, the treatment is also applied to the filter media holder, depending on the application. Filter media having at least two distinct surface property modifications are provided in liquid filtration applications to enhance the performance of a filtration system, reduce the cost of the system, provided a visual means of detecting fluid bypass, and minimize fluid holdup volume within the filter media, all with substantially no loss of performance performances parameters, even in steam sterilization applications.