Abstract: A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming the microprotrusions to a patient's palm in order to enable uniform penetration of the microprotrusions into the corneum.
Type:
Grant
Filed:
November 16, 2006
Date of Patent:
June 24, 2008
Assignee:
Allergan, Inc.
Inventors:
Orest Olejnik, Robert T. Lyons, Scott J. Gerondale
Abstract: Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
Type:
Grant
Filed:
January 15, 2003
Date of Patent:
April 1, 2008
Assignee:
Allergan, Inc.
Inventors:
David F. Woodward, Amanda M. VanDenburgh
Abstract: A method and composition for potentiating the effects of neuroleptic drugs by administering to a human having a disorder normally treatable with a neuroleptic drug, a neuroleptic drug in combination with a potentiating amount of an amino acid of the formula ##SPC1##Where R is fluorine, chlorine, bromine or trifluoromethyl and their salts.