Abstract: The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.

Abstract: The present invention relates to 1,4-benzodiazepin-2-ones of Formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present invention relates to compounds of formula I: or pharmaceutically acceptable salt forms or prodrugs thereof, which are useful as inhibitors of HIV protease, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.

Abstract: The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.

Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present invention relates to processes for the conversion of nitrites to amidines in the preparation of compounds which are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex. The compounds described herein are potent thrombolytics and useful for the inhibition of platelet aggregation in the treatment of thromboembolic disorders.

Abstract: The present invention relates to benzoxazinones of formula I: ##STR1## or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: ##STR1## or steroisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent, wherein:R.sup.1 is C.sub.1-3 alkyl substituted with 1-7 halogen;R.sup.2 is optionally substituted C.sub.1-5 alkyl, optionally substituted C.sub.2-5 alkenyl, or optionally substituted C.sub.2-5 alkynyl;R.sup.3, at each occurrence, is independently selected from C.sub.1-4 alkyl, OH, C.sub.1-4 alkoxy, F, Cl, Br, I, NR.sup.5 R.sup.5a, NO.sub.2, CN, C(O)R.sup.6, NHC(O)R.sup.7, and NHC(O)NR.sup.5 R.sup.5a ;R.sup.5 and R.sup.5a are independently selected from H and C.sub.1-3 alkyl;R.sup.6 is selected from H, OH, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, and NR.sup.5 R.sup.5a ;R.sup.

Abstract: The invention is directed to an electrical connector having an outer metal shell with an inner dielectric insert and a central contact pin received within the dielectric insert. The outer metal shell has a mating end with forward passageway. The outer metal shell has a dielectric insert receiving passageway which is narrower than the forward passageway. A shoulder is disposed along the inner wall between the forward passageway and the dielectric insert receiving passageway. The shoulder being angled towards the forward passageway. The shoulder is deformable over the dielectric insert to secure the dielectric insert within the outer metal shell.

Abstract: A connector (24) is disclosed for electrically interconnecting a component (14) to circuitry within a cabinet (10), where the component is arranged to slide in and out of a bay (12) in the cabinet (10). The connector (24) is attached to the component (14) and includes an insulated housing (40) having a plurality of electrical contacts (60) arranged therein. The contacts (60) are adapted for mating along a first mating axis (23) of the connector with respective ones of other electrical contacts (100) in a mating connector (26) attached to the cabinet (10). The contacts (60) of the connector (24) are further adapted for mating along a second mating axis (74), that forms a right angle to the first mating axis (23), with respective ones of individual contacts (158) attached to individual wires (156) that are secured to the cabinet (10).

Abstract: An electrical contact for an electrical connector assembly having a detached is specified latching tongue for latching in a chamber, the latching tongue originating from a base of the contact, a supporting tongue being provided on it, in order to provide additional kinking protection for the latching tongue, the free end of the supporting tongue resting on the base and running against a stop.

Abstract: An electrical connector (20) having a cover (70) pivotally secured thereto includes a housing (22) having a base (42), opposed side walls (26), and end walls (32), together defining a terminal receiving cavity (68) and a plurality of terminals (90) disposed in at least two rows therein. The cover (70) includes a hinge receiving slot (76) extending along a common one of its elongate sides (72) and inwardly from each end thereof. The cover (70) is secured to the housing (22) by a pair of hinges (78) with a base (80) of each hinge retained within in a respective one of the cover slots (76) and the leading end (84) of a leg (82) of each hinge (78) pivotally mounted proximate a middle position of a respective one of the housing end walls (32) adjacent an entrance to the cavity (68).

Abstract: An isolating switch for an electric power line including a sub-assembly made up of two electrically conductive and pieces interconnected by at least one insulator. The end pieces have respective aligned grooves for registry with the electric power line, and securing members for permanently securing the end pieces to the electric power line. The sub-assembly is provided with two keeper bars for mounting the sub-assembly to the power line prior to permanently securing the end pieces to the power line. Each of the keeper bars is pivotally mounted on a respective one of the end pieces and is pivotable manually between a first position in which the keeper bar is completely clear of the groove and a second position in which the keeper bar extends across the groove to retain the sub-assembly on the power line.

Abstract: A machine (40) is disclosed for crimping a terminal (12) onto a wire (10) thereby forming a crimped wire assembly (32). The machine includes a crimping bar 64 and a mating anvil (60) for performing the crimping operation. A terminal feed unit (70) is provided for feeding a strip (24) of terminals. The machine includes a wire guiding device (80) having an upper half (82) attached to the crimping bar (64) and a lower half (84) attached to the anvil (60). Each of the upper and lower halves include two wire guide members (88) that slide toward and away from a central axis (116) extending through the barrel (22) of the terminal (12) to be crimped. The ends of the four wire guide members (88), each having a quarter of a conical surface (118) formed thereon, are arranged so that the four surfaces form a complete conical section for guiding the wire (10) as it is being inserted into the barrel (22) of the terminal (12).

Abstract: The invention comprises an electrical connector assembly for connecting a daughter card to a mother board including a first housing (20) having contacts (34, 38) mounted therein. The contacts (34, 38) are electrically connected to the daughter card. A second housing (24) is mounted along the edge of the daughter card. The second housing (24) has a mating face and a connecting face. The second housing has contacts (90, 92) mounted therein. The contacts (90, 92) of the second housing are electrically connected to the contacts (34, 38) in the first housing by an impedance controlled flexible film (110). The mating face has a plurality of contact protrusions (88) forming a field. The contact protrusion (88) have one ground contact (92) disposed along one side and two signal contacts (90) disposed along another side to form a differential pair for engaging contacts (126, 128) on the motherboard.

Abstract: The present invention is directed to a process for forming a layer of palladium on a substrate, comprising:preparing a solution of a palladium precursor, wherein the palladium precursor consists ofPd(OOCR.sup.1).sub.m (OOCR.sup.2).sub.nwhereinR.sup.1 is hydrogen, alkyl, alkenyl, alkynyl, --R.sup.3 COOH, alkyl from 1 to 5 carbons substituted with one or two hydroxyl groups,R.sup.2 is hydrogen, alkyl, alkenyl, alkynyl, --R.sup.3 COOH, alkyl from 1 to 5 carbon atoms substituted with one or two hydroxyl groups, --CHO,R.sup.3 is alkyl, and alkyl groups from 1 to 5 carbon atoms substituted with one or two hydroxyl groupsm and n are real numbers or fractions, and m+n=2;applying the palladium precursor to the surface of the substrate;decomposing the palladium precursor by subjecting the precursor to heat.

Abstract: An electrical connector (20) includes a dielectric housing (22) having a mating face (24) and a pair of contacts (44,54) disposed therein. Each contact (44,54) has a contact section (46,56) exposed at the mating face (24). The first contact section (46) is associated with a forwardly extending shroud (26) spaced from and circumscribing the first contact section (46). The second contact section (56) is associated with a forwardly extending silo (28) closely surrounding the second contact section (56). The second contact section (56) is complementary to the first contact section (46) and the silo (28) is complementary to the shroud (26), whereby the connector mating face (24) is hermaphroditic.

Abstract: A detector unit (30) for use in a wire handling machine (10) includes an encoder (38) for monitoring movement of the wire (26) along a wire feed path (28) and for detecting the presence of a splice (130) and the end of the wire (26) as it is being fed. The shaft (58) of the encoder is electrically interconnected to the frame (12) of the machine by means of a brush (66) and leaf spring (68) and includes an enlarged diameter (62) for engaging and being driven by the wire being fed. A presser member (84), which is electrically isolated from the frame (12), is arranged to urge the wire against the enlarged diameter (62) so that when a the wire is fed it causes the shaft (58) of the encoder to rotate proportionately. When the controller unit (126) detects wire movement that is substantially different from that expected, the machine is stopped and an appropriate message is displayed.

Abstract: A hand tool (10) is provided for crimping an electrical terminal onto a conductor. The tool includes a frame (12) having a fixed crimping tool (14) secured at one end and a movable crimping tool (16) arranged to slide along a linear path (20) within a guideway (48) in the frame (12) toward and away from the fixed crimping tool (14). A lever (18) is pivotally coupled to the movable crimping die (16) by a drive link (144) and three pivotal attachments (128, 146, 152). The drive link (144) includes a ratchet surface (188) in engagement with a pawl (196) pivotally attached to the lever (18) for compelling continued movement of the lever once a crimping operation has begun.