Abstract: The present invention relates to the discovery of novel proteins of mammalian origin which are immediate downstream targets for FKBP/rapamycin complexes and provides, e.g., isolated polypeptides, nucleic acids encoding such, antibodies, screening methods, and diagnostic and therepeutic methods.
Type:
Grant
Filed:
January 23, 1998
Date of Patent:
October 15, 2002
Assignee:
Ariad Pharmaceuticals
Inventors:
Vivian Berlin, Maria Isabel Chiu, Guillaume Cottarel, Veronique Damagnez