Patents Represented by Attorney, Agent or Law Firm Matthew M. Catlett
  • Variation in drug response related to polymorphisms in &bgr;2-adrenergic receptor
    Patent number: 6797472
    Abstract: A method for predicting an individual's response to the &bgr;-agonists salmeterol, albuterol, metaproterenol, terbutaline and formoterol is disclosed. Individuals expressing the Ile164 &bgr;2AR variant are likely to exhibit a reduced response as compared to individuals expressing the Thr164 &bgr;2AR variant. The method is useful for making treatment decisions for patients suffering from asthma and chronic obstructive pulmonary diseases.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: September 28, 2004
    Assignees: Genaissance Pharmaceuticals, Inc., University of Cincinnati
    Inventor: Stephen B. Liggett