Abstract: An arrangement for managing cables of accessories such as earphone sets, chargers, and synchronization arrangements used with portable electronic devices is provided by a flexible and elastically deformable loop that extends from a base that optionally includes a hook or other loop retention feature. The base may be alternatively configured to be integrally formed with a component of an accessory, or be configured as a discrete clip that may be detachably coupled to the component, or to the cable portion of the accessory. The elastically deformable loop is configured to be removably fastenable by a user to articles such as buttons on clothing to help keep cables out of the way when the accessory is in use. In addition, the elastically deformable loop may be used to keep an accessory cable neatly stowed during storage by being stretched around a bundled cable and then secured on the hook.

Abstract: This invention is directed to a coating for a medical device, such as an intravascular stent, in which the coating, which comprises a first coating region comprising an adhesion promoter and a therapeutic agent. The coating can also include a second coating region which is substantially free of the adhesion promoter or any adhesion promoter. The invention is also directed to a method for manufacturing such a coated medical device.

Abstract: A kit for treating a gastrointestinal tract of a mammal and including a package and a tubular needle, an end piece and a container of an implant-forming material carried within the package. The end piece has an outer surface provided with at least one recess and an internal passageway communicating with the recess. The end piece is mounted on the distal extremity of an elongate probe member and introduced into the upper portion of the gastrointestinal tract. A portion of the wall of the gastrointestinal tract is drawn into the recess and the tubular needle is extended through the elongate probe member and the internal passageway into the portion of the wall in the recess. Material from the container is loaded into the tubular needle and injected into the portion of the wall to form an implant in the wall.

Abstract: This invention relates to devices and methods for the local, differential delivery of nitric oxide within the body. The devices include devices having at least two differing nitric oxide donor compounds, such as nitric oxide donor compounds having differing half-lives and nitric oxide donor compounds having different release mechanisms. The devices also include devices having at least two chemically distinct compositions to which nitric oxide donor compounds are adsorbed or attached or within which the donor compounds are disposed. The devices are typically used to increase local nitric oxide concentration in the body upon placement of the medical article at a delivery position on or within a patient.

Abstract: The present invention provides a medical device comprising a release region and a therapeutic agent disposed within or beneath the release region, and the release region includes a copolymer comprising a low Tg block and at least one graft copolymer endblock having a main chain and a plurality of side chains.