Abstract: The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle conjugates and methods for their preparation. The invention also relates to methods of detection of biomolecules comprising the biomolecule-core/shell nanoparticle conjugates.
Type:
Grant
Filed:
May 22, 2002
Date of Patent:
December 12, 2006
Assignee:
Nanosphere, Inc.
Inventors:
Chad A. Mirkin, Yun-Wei Cao, Rongchao Jin