Abstract: A shear spring comprising a base and a V-shaped surface opposite the base adapted to mate with a corresponding V-shaped surface positioned on a side wall of a spring mount, and an elastomeric material positioned between the base and the V-shaped surface, wherein the base includes a first flange extending away from the V-shaped surface and adapted to be positioned outwardly from a first edge of a side wall of a spring module, and wherein the base includes a second flange extending away from the V-shaped surface and adapted to be positioned outwardly from a second edge of the side wall of the spring module, where the first flange and the second flange are positioned in parallel planes.

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

Abstract: A tie-plate comprising a lower mounting flange that is removably attachable to a first frame hanger and to a second frame hanger, wherein the lower mounting flange includes a first set of attachment holes that correspond to a set of attachment holes at the first frame hanger, wherein the lower mounting flange includes a second set of attachment holes that correspond to a set of attachment holes at the second frame hanger, an extending member having a first end that extends at an angle from the lower mounting flange; and an upper mounting flange extending from a second end of the extending member, wherein the upper mounting flange has one or more mounting holes adapted for attachment of the tie-plate to an undercarriage of a vehicle.

Abstract: A vehicle suspension including a spring module and a spring mount positioned within an opening in the spring module with two shear springs on either side of the spring mount, wherein the spring mount includes an inboard part and an outboard part, and a through-hole positioned in the inboard or outboard part to allow passage of a threaded connecting rod therethrough that has been tightened to draw the inboard part of the first spring mount together with the outboard part of the first spring mount, and to compress the first shear spring between a first side wall of the spring mount and a first side wall of the opening, and also to compress a second shear spring between a second side wall of the spring mount and a second side wall of the opening.

Abstract: A haemolysator having a sonotrode plate and oscillation generating elements acting thereupon, wherein the oscillation generating elements are set into mechanical oscillations by an electrical AC-signal generator. The haemolysater also includes a sample chamber to which the sonotrode plate transmits mechanical oscillations, and has oscillation generating elements that are excitable toward mechanical oscillations in a wide frequency band.

Abstract: A vehicle suspension including a frame attachment portion attached to spring module having an opening defined by two side walls, a top wall and a bottom wall, and a spring mount positioned within the opening with two shear springs on either side of the spring mount, wherein the spring mount includes an inboard part and an outboard part separate from the inboard part, and a through-hole positioned in at least one of the inboard or inboard parts to allow passage of a threaded connecting rod therethrough, wherein the connecting rod has been tightened to draw the inboard part of the first spring mount together with the outboard part of the first spring mount, and to compress the first shear spring between the first side wall of the spring mount and the first side wall of the opening, and also to compress the second shear spring between the second side wall of the spring mount and the second side wall of the opening of the spring module.

Abstract: Photoactivatable prepolymers and methods of use thereof are disclosed for microencapsulation of a substantially water-insoluble material within a nonporous shell. As provided herein, the microencapsulated material is released with no more than a slow release rate. Upon exposure of the nonporous shell to light, the nonporous shell is converted into a porous shell having an increased release rate for the microencapsulated material.

Abstract: The invention relates to an antibody molecule having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing circuit breakers having a bottom housing and a top housing with a labyrinth seal or joint formed therebetween, the bottom housing adapted to receive one or more circuit breakers, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of a circuit breaker when placed within the bottom housing, and a first vent positioned on the top housing for dissipating pressure buildup, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of a circuit breakers within the housing.

Abstract: This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Abstract: The invention provides methods for detecting tumor-associated RNA in plasma, serum, and other bodily fluids. In particular, the invention provides methods for detecting translocated gene RNA, including fusion gene RNA, in plasma or serum or other bodily fluids.

Abstract: Bi-cistronic plasmids used for the expression of formate dehydrogenase (FDH) and modified phenylalanine dehydrogenase (PDHmod) are provided.

Abstract: An elastomeric spring suspension is described for supporting a longitudinally extending vehicle frame rail above first and second axles forming a tandem axle configuration. The suspension includes a frame hanger assembly mounted to the vehicle frame rail. The frame hanger assembly has two full spring modules, each of which includes two shear springs, a progressive spring rate load cushion having a pyramidal shape with a flattened top surface and a spring mount for mounting the springs. A saddle assembly is connected to the spring mount, and an equalizing beam is connected to the saddle assembly and further connected to the axles. The spring rate for the suspension increases almost linearly as a function of sprung load, resembling a pneumatic suspension. Accordingly, the suspension exhibits excellent ride quality, without sacrificing roll stability.

Abstract: This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of these antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Abstract: The present invention provides stereoisomers and stereoisomeric mixtures of 3-aminocarbonyl-bicycloheptene-2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.

Abstract: An improved monopole antenna for in-duct use is disclosed. The antenna comprises a center pin rod disposed coupled to a connector housing by a molded dielectric. The center pin rod includes a pin portion which is disposed through a portion of a connector portion of the connector housing, thereby allowing a mating RF connector to couple to the monopole antenna. The center pin rod is composed of a single assembly or a single piece of material, thereby eliminating the need to solder the antenna to a RF connector.