Abstract: The present invention provides methods of utilizing a nucleoside derivative having the chemical formula of Formula (I) to downregulate expression of an anti-apoptotic protein such as survivin in a cell, induce apoptosis in a cell, inhibit angiogenesis in a cell, inhibit binding of p53 to DNA in a cell, inhibit phosphorylation of Akt in a cell and inhibit HIV transcription in a cell, by administering to the cell or tissue an amount of a compound of Formula (I) sufficient to achieve the desired activity. Formula (I): wherein the substituents Ra, Rb, Rc, Rd, Re, Rf, Rg, Rh, Ri and Rk are as defined in the specification. A particularly preferred nucleoside derivative is ARC (4-amino-6-hydrazino-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carboxamide).

Abstract: The present invention provides methods and pharmaceutical formulations for treating diabetic foot ulcers.

Abstract: In the manufacture of electronic devices that use porous dielectric materials, the properties of the dielectric in a pristine state can be altered by various processing steps. In a method for restoring and preserving the pristine properties of a porous dielectric layer, a substrate is provided with a layer of processed porous dielectric on top, whereby the processed porous dielectric is at least partially exposed. A thin aqueous film is formed at least on the exposed parts of the processed porous dielectric. The exposed porous dielectric with the aqueous film is exposed to an ambient containing a mixture comprising at least one silylation agent and dense CO2, resulting in the restoration and preservation of the pristine properties of the porous dielectric.

Abstract: System and methods for a price feed generation are described. According to an example method described herein, upon receiving market information including a plurality of linear prices and order quantities, a reference price level is selected and a price feed message is generated to include the reference price level and the plurality of order quantities. The price feed message is then provided to client terminals.

Abstract: Disclosed are systems, methods, and devices for interfacing with a wearable heads-up display via a finger-operable input device. The wearable heads-up display may include a display element for receiving and displaying display information received from a processor, and may also include a wearable frame structure supporting the display element and having a projection extending away from the display element. The projection may be configured to secure the heads-up display to a user's body in a manner such that the display element is disposed within a field of view of the user. A finger-operable input device secured to the wearable frame structure is configured to sense at least one of a position and movement of a finger along a planar direction relative to a surface of the input device, and to provide corresponding input information to the processor.

Abstract: An example graphical interface and method for displaying risk related data are described. One example graphical interface includes a data structure comprising a plurality of data nodes and at least one risk data point associated with each node, and further comprises a display grid. The display grid includes one or more cells that are used for displaying selected data nodes and risk data points. Each cell may be associated with a single data node, and may include one or more identifiers corresponding to risk data points of the data node. In one example embodiment, the identifiers are aligned along a single axis, and risk related data corresponding to each identifier is aligned with respect to each corresponding identifier.

Abstract: Example methods and systems are disclosed that utilize optical-flow analysis to help recognize the performance of a predetermined user-action by a user of a wearable computer, such as a user-action for selecting an object within the user's view. An example method may involve a wearable computing device: (a) receiving a video from a video camera of a wearable computing device: (b) determining optical flow for the video; (c) determining that an optical-flow differential exists at an area within the optical flow for the video; and (d) responsive to determining that the optical-flow differential exists at the area within the optical flow: (i) identifying an object that is located at the area where the optical-flow differential exists; (ii) performing a search on the object that is located at the area where the optical-flow differential exists; and (iii) causing a graphical display to display information that corresponds to results from the search.

Abstract: Methods and apparatus for creating and controlling transient cavitation are disclosed. An example method includes selecting a range of bubble sizes to be created in a liquid and selecting characteristics for an acoustic field to be applied to the liquid. The method further includes creating gas bubbles of the selected range of bubble sizes in the liquid, creating an acoustic field with the selected characteristics and subjecting the liquid to the acoustic field. In the example method, at least one of the range of bubble sizes and the characteristics of the acoustic field is selected in correspondence with the other so as to control transient cavitation in the liquid for the selected range of bubble sizes. Particularly, the methods and apparatus may be used for the cleaning of a surface, such as a semiconductor substrate.

Abstract: Trading software may receive trading information from an exchange. The trading software may use the trading information to compute an estimate of last traded total sweep quantity. The trading software may also display the last traded total sweep quantity on a trading screen.

Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

Abstract: A method for applying reactive films containing solids to microporous membranes is provided wherein the membrane is firstly moistened and the reactive film containing solids is applied to the membrane while it is still moist. Membranes produced in this manner can contain reactive films having a high proportion of film openers and can be used advantageously in diagnostic elements for detecting constituents and, in particular, large hydrophobic analytes in body fluids.

Abstract: The present invention relates to processes and continuous processes for preparing gaseous products, and in particular, methane via the catalytic gasification of carbonaceous feedstocks in the presence of steam. In one aspect of the invention, the processes comprise at least partially combusting a first carbonaceous feedstock with an oxygen-rich gas stream, a recycle steam stream, and an aqueous make-up stream in an oxygen-blown gasifier, under suitable temperature and pressure, to generate a first gas stream comprising hydrogen, carbon monoxide and superheated steam; and reacting a second carbonaceous feedstock and the first gas stream in a catalytic gasifier in the presence of a gasification catalyst under suitable temperature and pressure to form a second gas stream comprising a plurality of gaseous products comprising methane, carbon dioxide, hydrogen, carbon monoxide and hydrogen sulfide.

Abstract: A vehicle arresting device comprises a net intended to be laid flat on the ground in the path of an oncoming vehicle to be arrested. Two rows of barbed spikes are attached to the net along its leading edge. When a vehicle runs over the device the spikes lodge in its front tires and the net is caused to wrap around the front wheels, eventually being pulled tight under the vehicle so that the tension in the net prevents further rotation of the wheels and the vehicle is brought to a stop. The net is manufactured such that in its deployed condition it has sufficient lateral stretch to allow it to become fully wrapped around the front wheels before the tension builds up to a level at which there might otherwise be a risk of the spikes being pulled from the tires.

Abstract: This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-?) and methods for treating IFN-? mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-?. Methods of detecting the amount of IFN-? in a sample using antibodies to IFN-? are also provided.

Abstract: The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies.

Abstract: The present invention relates to the use of at least one compound of formula (I) R—(OCH2)n—OR? in which R and R?, identical or different, represent a linear or branched alkyl radical comprising 1 to 5 carbon atoms and n is an index with a value comprised between 1 and 8, and/or at least one dialdehyde acetal type compound for the preservation of the human or animal body and/or the embalming of dead bodies. It also relates to a composition comprising same and a process for preserving a human or animal body and/or embalming a dead body comprising the administration of the composition to the dead body in particular by injection, perfusion, immersion or topical application.

Abstract: An image forming system includes a plurality of image forming apparatuses and an information processing apparatus connected to a network. Each image forming apparatus includes a remaining-toner sensor for detecting remaining amounts of toner in cyan (C), magenta (M), yellow (Y), and black (K) toner cartridges. The information processing apparatus includes (i) a storage device for storing various types of information obtained from the image forming apparatuses, including apparatus status information such as the remaining amounts of toner, and (ii) a display device for displaying icons representing the remaining amounts of C/M/Y/K toners in a line on a respective apparatus basis, and displaying the icons representing the remaining amounts of C/M/Y/K toners for all of the plurality of image forming apparatuses in lines on a respective color basis so that said lines are perpendicular to said line in which the icons representing the remaining amounts of toner are displayed.

Abstract: This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Abstract: Methods are apparatuses are described for identifying a target object using optical occlusion. A head-mounted display perceives a characteristic of a reference object. The head-mounted display detects a change of the perceived characteristic of the reference object and makes a determination that a detected object caused the change of the perceived characteristic. In response to making the determination, the head-mounted display identifies the detected object as the target object.

Abstract: A computing device may select a source tile from a source image. From the source tile, the computing device may select a first rectangular feature and a second rectangular feature. Based on the first and second rectangular features, the computing device may calculate a source feature vector. The computing device may also select a search area of a target image, and a target tile within the within the search area. Based on the target tile, the computing device may calculate a target feature vector. The computing device may determine that a difference between the source feature vector and the target feature vector is below an error threshold, and based on this determination, further determine a mapping between the source image and the target image. The computing device may then apply the mapping to the source image to produce a transformed source image.