Patents Represented by Attorney, Agent or Law Firm McDonnell, Boehnen, Hulbert & Berhoff
  • Patent number: 6175015
    Abstract: Disclosed are compounds of the formula: or the pharmaceutically acceptable acid addition salts thereof wherein: R1 and R2 are the same or different and represent hydrogen, C1-C6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C1-C6 alkoxy, —O2CR′, —NHCOR′, —COR′, —SOmR′, where R′ is C1-C6 alkyl and wherein m is 0, 1 or 2; or R1 and R2 independently represent —CONR′R″, or —NR′R″ where R′ and R″ independently represent hydrogen or C1-C6 alkyl; R3 is hydrogen, C1-C6 alkyl, or —COR′″ where R′″ is C1-C6 alkyl; R4 is hydrogen or C1-C6 alkyl; and R represents an azacycloalkylalkyl group, which compounds are useful in the treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parkinsonism and dysronia, and other disorders which respond to dopaminergi
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: January 16, 2001
    Assignee: Neurogen Corporation
    Inventors: Jun Yuan, Jan Wasley