Patents Represented by Attorney McDonnell Boehnen Hulbert & Uerghoff LLP

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  • Tetrapeptide inhibitors of ?-secretase
    Patent number: 7169759
    Abstract: Statine-derived peptide inhibitors of the ?-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A? peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce A? peptide formation and pharmaceutical compositions.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: January 30, 2007
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Varghese John, Jay Tung, Lawrence Fang, Shumeye S. Mamo