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  • Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates
    Patent number: 6951946
    Abstract: Disclosed are efficient and scalable processes for preparing 1,2,4- and 1,3,4-oxadiazole carboxylates from readily available starting materials.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: October 4, 2005
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hartmuth C. Kolb, Ramanaiah C. Kanamarlapudi, Paul F. Richardson