Abstract: The invention provides genetic suppressor elements that confer the transformed phenotype of malignant mammalian cells upon untransformed cells, methods for identifying and obtaining such elements, methods for isolating and identifying genes corresponding to such elements, and methods of using such elements. The invention also provides genes corresponding to the GSEs of the invention.
Type:
Grant
Filed:
October 12, 1999
Date of Patent:
March 6, 2001
Assignee:
University of Illinois
Inventors:
Andrei Gudkov, Alexander Kazarov, Ilya Mazo, Igor B. Roninson