Abstract: A sampling system includes a collection module including a gas handler, and a flow controller in communication with the gas handler of the collection module. The flow controller controls the gas handler to move a selected volume of gas through the collection module.
Abstract: The present invention relates to a treatment by pulmonary delivery of bioscavengers to animals as an effective antidote to prevent toxicity produced by exposure of an animal to nerve agents and other toxic substances.
Abstract: Various solvent-assisted extrusion processes are disclosed that are suitable for forming high yield, low coarse content, polyester latexes that may be utilized in forming a toner.
Type:
Grant
Filed:
June 21, 2010
Date of Patent:
May 1, 2012
Assignee:
Xerox Corporation
Inventors:
Timothy L. Lincoln, John L. Pawlak, Brian J. Andaya, Joo T. Chung, Joseph L. Leonardo, Santiago Faucher, Shigang Qiu
Abstract: The present disclosure provides blue toners and methods for their production. In embodiments, methods of the present disclosure include systems which may be utilized to predict the color properties of a blue toner, thereby permitting adjustment of the pigment loading and/or toner mass per unit area.
Type:
Grant
Filed:
January 20, 2010
Date of Patent:
March 20, 2012
Assignee:
Xerox Corporation
Inventors:
Jordan H. Wosnick, Richard P. N. Veregin, Eric Rotberg
Abstract: Embodiments include a toner having a) a polyester resin derived from a naphthalenic material, a 2-alkyl succinic material, and 2,2-ethyl-butyl-1,3-propanediol, b) a wax, and c) an optional colorant.
Abstract: The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3?-terminal stretch of nucleotides of the first stretch Box A hybridizes with the second stretch Box B, whereby upon hybridization a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge.
Type:
Grant
Filed:
April 7, 2006
Date of Patent:
January 24, 2012
Assignee:
NOXXON Pharma AG
Inventors:
Florian Jarosch, Dirk Eulberg, Christian Maasch, Steffen Helmling, Sven Klussmann
Abstract: The present disclosure provides processes for producing images of excellent color fidelity when incorporating a magenta toner with a lower colorant loading in addition to a first magenta toner. In embodiments, the magenta pigmented particles may be magenta emulsion aggregation toners. In accordance with the present disclosure, a pair of magenta toners are matched in color, wherein the color of a first magenta toner printed at a predetermined halftone area coverage on a substrate substantially matches the color of the solid (100%) printed patch of the second magenta toner, which is lighter than the first magenta toner, thus avoiding a visible hue shift on the print that would otherwise be objectionable.
Type:
Grant
Filed:
January 19, 2010
Date of Patent:
January 10, 2012
Assignee:
Xerox Corporation
Inventors:
Daryl W. Vanbesien, Karen Ann Moffat, Yi Xin Gong, Edul N. Dalal, Jing Wang, Richard P. N. Veregin, Jordan H. Wosnick, Cuong Vong, Valerie M. Farrugia
Abstract: Toner particles are provided which may, in embodiments, include a core and a shell formed in situ. The resins utilized to form the core, the shell, or both, may be contacted with a water soluble initiator. The resin, in embodiments present in the shell, cross-links at a temperature near the temperature for coalescence, and may prevent a crystalline resin in the core from migrating to the toner surface.
Type:
Grant
Filed:
August 27, 2008
Date of Patent:
January 10, 2012
Assignee:
Xerox Corporation
Inventors:
Ke Zhou, Edward G. Zwartz, Karen Ann Moffat
Abstract: The present disclosure provides processes for reducing the particle size of latex resins and toners produced with such resins. In embodiments, a gel latex may be formed as a seed particle and then utilized to form latex resins and toner particles. In accordance with the present disclosure, one may be able to utilize materials for the production of latex resins and toners which may otherwise produce particles that are too large in the absence of the gel latex.
Type:
Grant
Filed:
April 21, 2008
Date of Patent:
January 10, 2012
Assignee:
Xerox Corporation
Inventors:
Zhen Lai, Chieh-Min Cheng, Robert D. Bayley, Grazyna E. Kmiecik-Lawrynowicz, Maura A. Sweeney, Daniel G. Marsh, Emily L. Moore, Shigang Qiu, Tie Hwee Ng
Abstract: The invention concerns nucleic acids coding for mutated or truncated forms of the human parkin gene, or forms comprising multiplication of exons, and the corresponding proteins and antibodies. The invention also concerns methods and kits for identifying mutations of the parkin gene, and for studying compounds for therapeutic purposes.
Type:
Grant
Filed:
November 18, 1999
Date of Patent:
August 16, 2011
Assignees:
Aventis Pharma S.A., Institut National Sante et Recherche Medicale
Abstract: A method for the evaluation of target media parameters in the visible and near infrared is disclosed. The apparatus comprises a light source, an illuminator/collector, optional illumination wavelength selector, an optional light gating processor, an imager, detected wavelength selector, controller, analyzer and a display unit. The apparatus illuminates an in situ sample of the target media in the visible through near infrared spectral region using multiple wavelengths and gated light. The sample absorbs some of the light while a large portion of the light is diffusely scattered within the sample. Scattering disperses the light in all directions. A fraction of the deeply penetrating scattered light exits the sample and may be detected in an imaging fashion using wavelength selection and an optical imaging system.
Abstract: The invention relates to an antagonist for CGRP and amylin, whereby the antagonist is a nucleic acid and said nucleic acid binds to CGRP or amylin. Said nucleic acid preferably comprises an L-nucleotide.
Type:
Grant
Filed:
May 6, 2003
Date of Patent:
February 1, 2011
Assignee:
NOXXON Pharma AG
Inventors:
Axel Vater, Christian Maasch, Florian Jarosch, Mathias Bell, Steffen Helmling, Bernd Eschgfäller, Elisabeth Moyroud, Sandra Stark, Sven Klussmann, Thorsten Ruppert, Gregor Bahrenberg, Clemens Gillen, Klaus Schiene
Abstract: The present invention describes a method for producing butanol by fermentation of carbohydrates using mixed populations of acidogenic-phase cells and solventogenic-phase cells of Clostridium in a solitary vessel. The present system as described does not require intermittent adjustment of pH or venting of headspace gases. The method provides a process for removal of the butanol product which does not irreversibly harm the cells and conditions are described where such cells may resume butanol synthesis in the same solitary vessel. The invention also describes compositions and biologically pure cultures which comprise the Clostridium cells as disclosed. Also, a biologically pure Clostridium beijerinkii strain NRRL No. B-50244 is disclosed.
Abstract: This invention pertains to BIV constructs encompassing BIV combination vectors, BIV vectors and BIV packaging vectors and particularly the invention pertains to a three vector system comprising: a) a BIV vector construct including a DNA segment from a BIV genome, a packaging sequence to package RNA into virions; a promoter operably linked to the DNA segment; and a transgene operably linked to a second promoter; b) a BIV packaging vector construct comprising a BIV DNA sequence fragment comprising at least a gag gene or pol gene of BIV; a promoter operably linked to the BIV DNA fragment; and a polyadenylation sequence located downstream of the BIV DNA fragment; and c) an expression vector construct comprising a gene encoding a viral surface protein. Also provided is a method for transferring a gene of interest into a mammalian cell.
Type:
Grant
Filed:
March 8, 2005
Date of Patent:
August 31, 2010
Assignee:
Novartis AG
Inventors:
Tianci Luo, Robert Berkowitz, Michael Kaleko
Abstract: A method for clarifying an image of an object to perform a procedure on an object includes applying electromagnetic energy to the object to provide reflected and/or transmitted energy according to an interaction of the electromagnetic energy and the object, determining an image quality metric in accordance with the reflected and/or transmitted energy to provide a determined image quality metric, determining an image in accordance with the determined image quality metric to provide a determined image, and performing the procedure in accordance with the image quality metric and the determined image.
Abstract: Asymmetrically branched polymers are combined with bioactive agents for a variety of purposes including drug delivery and conjugation to one member of a binding pair for use in an assay.
Abstract: The present invention is related to an antagonist of ghrelin, wherein the antagonist is a nucleic acid, and whereby preferably the nucleic acid is binding to ghrelin.
Type:
Grant
Filed:
August 1, 2003
Date of Patent:
July 6, 2010
Assignee:
NOXXON Pharma AG
Inventors:
Steffen Helmling, Dirk Eulberg, Christian Maasch, Sven Klussmann
Abstract: An economical process for in vivo production of the pigment astaxanthin, and particularly a process for enhancing astaxanthin content of cultures of microorganisms of genus Phaffia, the process comprising culturing a microorganism of genus Phaffia in a nutrient medium containing an antibiotic, a cytochrome B inhibitor, or a terpenoid synthetic pathway inhibitor, cultivating surviving pigment enhanced microorganisms, and harvesting the yeast.
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
May 25, 2010
Assignee:
Igene Biotechnology, Inc.
Inventors:
Eric A. Johnson, Huei-hsiung Yang, Beril Geldiay-Tuncer, William T. Hall, David Schreiber, Kwok Ho
Abstract: The present invention provides novel lentiviral packaging constructs that are useful for the establishment of stable packaging cell lines and producer cell lines. In particular, the present invention provides novel packaging cell lines that are capable of constitutively expressing high levels of lentiviral proteins.
Type:
Grant
Filed:
June 30, 2006
Date of Patent:
April 20, 2010
Assignee:
Novartis AG
Inventors:
Michael Kaleko, Tianci Luo, Ivan Plavec, Janet Lynn Douglas