Abstract: The device for heating a drinkable liquid, having a liquid-storage container (9) and an electric heating element (11) arranged therein, the liquid-storage container (9) having a valve which is arranged at the bottom in the base (12) of the liquid-storage container (9) and of which one sealing surface is the border of an opening (14) in the base (12) and which opens, in a manner which cannot automatically be reversed, on account of the base curving outwards at a predetermined internal pressure in the container, and the power supply to the heating element (11) being designed such that it is interrupted when the pressure in the liquid-storage container (9) is essentially equal to the atmospheric pressure, which device can be positioned on a collecting container for the liquid, is distinguished in that the other sealing surface of the valve is a plate-like element (15) which consists of elastic material and, in its non-loaded state, is shaped essentially conically, with the cone tip directed towards the interior
Abstract: The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, .beta.-galactosidase activity is utilized as a means by which cell senescence may be assessed either in vitro cell cultures or in vivo.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
August 18, 1998
Assignee:
The Regents of the University of California
Inventors:
Goberdhan P. Dimri, Judith Campisi, Monica Peacocke