Abstract: The present invention provides a method for identifying inhibitors of protein kinases and/or protein phosphatases. Methods are also provided for inhibiting protein kinase and/or protein phosphatase activity. Specific non-peptide protein tyrosine kinase and/or protein phosphatase inhibitors are provided. The protein kinase or protein phosphatase inhibitors of the present invention may be used to treat a number of conditions in patients, including cancer, psoriasis, arthrosclerosis, immune system activity, Type II diabetes, and obesity.
Type:
Grant
Filed:
October 19, 2002
Date of Patent:
February 28, 2006
Assignee:
The Research Foundation of State University of New York
Inventors:
David G. Hangauer, Jr., Moustafa E. El-Araby, Karen L. Milkiewicz