Patents Represented by Law Firm Merchant, Gould, Smith, Smith, Edell & Welter
  • Patent number: 5846774
    Abstract: The present invention provides novel promoter sequences obtained from Chlorella virus. The invention includes gene constructs comprising a promoter sequence of the invention operably linked to a DNA sequence encoding a structural gene. The invention also provides vectors and host cells for expressing a product encoded by the structural gene of a gene construct of the invention and cells transformed with the heterologous gene operably linked to the promoter.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: December 8, 1998
    Assignee: BioNebraska, Inc.
    Inventor: Yuannan Xia
  • Patent number: 5762856
    Abstract: A system for generating three-dimensional objects by creating a cross-sectional pattern of the object to be formed at a selected surface of a fluid medium capable of altering its physical state in response to appropriate synergistic stimulation by impinging radiation, particle bombardment or chemical reaction, successive adjacent laminae, representing corresponding successive adjacent cross-sections of the object, being automatically formed and integrated together to provide a step-wise laminar buildup of the desired object, whereby a three-dimensional object is formed and drawn from a substantially planar surface of the fluid medium during the forming process.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 9, 1998
    Inventor: Charles W. Hull
  • Patent number: 5278202
    Abstract: A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body.
    Type: Grant
    Filed: December 23, 1991
    Date of Patent: January 11, 1994
    Assignee: Atrix Laboratories, Inc.
    Inventors: Richard L. Dunn, James P. English, Donald R. Cowsar, David D. Vanderbilt