Patents Represented by Law Firm Merchant, Gould, Smith, Welter & Schmidt
  • Patent number: 5869045
    Abstract: The present invention relates to novel antibodies, antibody fragments and antibody conjugates and single-chain immunotoxins reactive with human carcinoma cells. More particularly, the antibodies, conjugates and single-chain immunotoxins of the invention include: a murine monoclonal antibody, BR96; a human/murine chimeric antibody, ChiBR96; a F(ab').sub.2 fragment of BR96; ChiBR96-PE, ChiBR96-LysPE40, ChiBR96 F(ab').sub.2 -LysPE40 and ChiBR96 Fab'-LysPE40 conjugates and recombinant BR96 sFv-PE40 immunotoxin. These molecules are reactive with a cell membrane antigen on the surface of human carcinomas. The BR96 antibody and its functional equivalents, displays a high degree of selectivity for carcinoma cells and possess the ability to mediate antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity activity.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 9, 1999
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ingegerg Hellstrom, Karl Erik Hellstrom, Kim Folger Bruce, George J. Schreiber
  • Patent number: 5837204
    Abstract: A system for disinfecting the water lines of a dental unit is provided with first and second unidirectional check valves. Water at a first pressure is normally supplied to the water lines of the dental unit through the first check valve. A reservoir of liquid disinfectant can be pressurized at a second pressure higher than the first pressure by the air compressor already equipping the dental unit to supply disinfectant to the water lines of the dental unit through the second check valve. Liquid disinfectant is prevented from reaching the water supply line by the first check valve. In the same manner, when the reservoir is not pressurized, the second check valve prevents water from the water supply line from reaching the disinfectant.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: November 17, 1998
    Assignees: Universite de Montreal, Theratechnologies, Inc.
    Inventors: Andre Prevost, Jean Barbeau, Ludger Cote, Robert Charland, Gary Savage, Michel Swift
  • Patent number: 5673535
    Abstract: Apparatus for filling sterile containers is disclosed which defines an elongated but narrow sterile zone in which a number of operating stations are disposed. An elongated vertical wall is carried by an elongated frame and a cabinet type enclosure cooperates with the vertical wall to define the sterile zone. The plurality of operating stations are disposed in sequential relation over the length of the sterile zone, and an elongated container conveyor is disposed within the sterile zone to convey the containers through the plurality of operating stations. The conveyor is vertically oriented, consisting an endless belt mounted on end wheels that rotate on horizontal axes. Each of the operating stations includes an operating portion disposed within the sterile zone. Actuating means are included for each of the operating stations as well as the elongated conveyor, each of which is disposed outside the sterile zone.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: October 7, 1997
    Assignee: TL Systems Corporation
    Inventor: Theodore W. Jagger
  • Patent number: 5383879
    Abstract: An applicator for-applying bone wax to bone tissue in which a layer of bone wax covers selected surface portions of a pattie of surgical fibre, and a method of applying bone wax from an applicator having a layer of bone wax covering portions of a pattie wherein the bone wax layer is drawn across the bone to deposit the bone wax, and the deposited bone wax is then molded over the bone tissue with exposed portions of the applicator pattie.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: January 24, 1995
    Inventor: Arnold G. Phillips
  • Patent number: 5301806
    Abstract: The invention relates to a clean up bag, more particularly to a plastic bag that has a plastic glove which is heat sealed to one interior side of the bag. The glove has two thumbs so that it may be used by either left handed or right handed individuals. The bag is covered with a cut-resistant fabric such as Kevlar, and has a padding of fibrous material on the outside of the bag which absorbs any liquid surrounding or contained in the waste to be picked up. The bag also has a draw string closure on the top which pulls from either side. The bag is turned inside out once the waste has been cleaned up, and the draw strings used to close the bag for disposal.
    Type: Grant
    Filed: November 6, 1992
    Date of Patent: April 12, 1994
    Inventor: Mary Lou Olson
  • Patent number: 5190799
    Abstract: A floor mat (10) is provided which includes longitudinal rail sections (e.g., 16, 17) capable of being interconnected with other longitudinal rails to form a roll up floor mat or pedestrian walking surface. The rails include a plastic cushion layer (21) which can be coextruded onto the upwardly facing surface of an underlying rigid plastic rail core (8), with the cushion layer being softer than the rail core and forming an integral walking surface thereon. At least one living hinge (23) may be employed within the rail section for pivotal movement of the rail, allowing the floor mat to be rolled up.
    Type: Grant
    Filed: May 9, 1991
    Date of Patent: March 2, 1993
    Assignee: Reese Enterprises, Inc.
    Inventor: Chester W. Ellingson, III
  • Patent number: 5006781
    Abstract: An electrical generator system integrated controller device utilizing PID control and capable of regulating voltage or current, and frequency simultaneously. The device utilizes a micro-controller (30.1) to monitor the engine generator set (20), then determines the appropriate signal to deliver to the electrical generator set (20) to regulate the engine throttle (21) and the generator (22) field windings. The micro-controller (30.1) also provides for real and reactive load sharing with additional generator sets (40) while also providing for an integrated circuit interrupter module (500) to open the line from the generator (22) to the load bus (42). Additionally, serial communications (34) are provided as well as displays (35), meters (37), and operator input (36). Finally, the permissive paralleling module (700) provides that the engine electrical generator set (20) will not be allowed to be connected to the load bus (42) until standards of voltage and phase have been achieved for a set period of time.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: April 9, 1991
    Assignee: Onan Corporation
    Inventors: Mark H. Schultz, David J. Koenig
  • Patent number: 5002226
    Abstract: An electromechanical thermostat for controlling the on/off cycle of a heating/cooling unit. The thermostat has a temperature sensing element with a variable position according to the sensed temperature. Associated with the sensing element is a switch member that provides on/off signals in response to the position of the sensing element. The thermostat has mechanical heat anticipation to control the generation of the on/off signals. In the preferred embodiment the mechanical heat anticipation is accomplished by a stepper motor which varies the position of either the sensing element or switch member to simulate thermal heat anticipation. The thermostat also has a mechanical structure to reduce or eliminate thermostat droop. Preferably this structure includes a control circuit to detect the duty cycle of the heating/cooling unit and mechanically and automatically adjusts the thermostat set point.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: March 26, 1991
    Assignee: Honeywell, Inc.
    Inventor: Lorne W. Nelson
  • Patent number: 4980234
    Abstract: A method of improving epoxy resin compositions to provide a cured resin having improved glass transition temperature and toughness characteristics is provided. The method includes providing in an epoxy resin composition an effective amount of a substituted fluorene unit in the composition. The fluorene component acts as a chain extension agent and provides for increased glass transition temperature and less cross-link density. As a result, improved toughness occurs. In preferred applications a toughening agent is provided in the resin composition, to further enhance toughness. Preferred resin compositions, cured resins and methods of providing improved cured resins are also provided.
    Type: Grant
    Filed: December 15, 1988
    Date of Patent: December 25, 1990
    Assignee: Minnesota Mining and Manufacturing Co.
    Inventors: Carl J. Almer, William J. Schultz
  • Patent number: 4964188
    Abstract: The invention relates to a clean up bag, more particularly to a plastic bag that has a plastic glove which is heat sealed to one interior side of the bag. The glove has two thumbs so that it may be used by either left handed or right handed individuals. There is a padding of fibrous material on the outside of the bag which absorbs any liquid surrounding or contained in the specimen to be picked up. Additionally, the padding prevents the user from feeling the texture or heat of the specimen. The bag also has a draw string closure on the top which pulls from either side and has pleats on each side of the bag so that it may be easily turned inside out. Finally, the bag is cloudy or opaque so that the user cannot see the contents.
    Type: Grant
    Filed: July 6, 1989
    Date of Patent: October 23, 1990
    Inventor: Mary L. Olson
  • Patent number: 4783340
    Abstract: A uniform, continuous sanitizing film can be formed by simultaneously spraying a two-package aqueous sanitizing composition comprising in a first solution a quaternary ammonium salt compound and in a second solution a polymer containing acid functionality. The sprays are directed to areas of substantial overlap resulting in a reaction between the quaternary ammonium compound and the carboxylic acid functional polymeric compound resulting in formation of a water insoluble film.
    Type: Grant
    Filed: April 29, 1987
    Date of Patent: November 8, 1988
    Assignee: Ecolab Inc.
    Inventors: James A. McDonell, Richard B. Greenwald
  • Patent number: 4337670
    Abstract: A support structure (10), preferably a rotatable bed, pivotable between a generally horizontal use position and a generally vertical storage position is disclosed. A counterbalancing mechanism (20) which reduces the amount of force needed to rotate the support structure (10) is operatively connected to the support structure (10). A drive arm (70) driven by a motor mechanism (64) in a linear direction is also operatively connected to the support structure (10). The drive arm (70) is connected to the support structure (10) through a linkage apparatus. The linkage apparatus has linkage plates (82) pivotably connected to drive arm (70) and connecting plates (92) extending from the support structure (10). A T-shaped rod mechanism (102) is engaged by latch (116), rotatably connected to the linkage plates (82), and extends through a hole in frame member (14) of support structure (10) where a coil spring (124) is received about the rod mechanism (102).
    Type: Grant
    Filed: October 2, 1979
    Date of Patent: July 6, 1982
    Assignee: Sico Incorporated
    Inventor: Ronald R. Carlson
  • Patent number: D287716
    Type: Grant
    Filed: September 1, 1983
    Date of Patent: January 13, 1987
    Assignee: Onan Corporation
    Inventor: Steven J. Iverson
  • Patent number: D375313
    Type: Grant
    Filed: June 13, 1995
    Date of Patent: November 5, 1996
    Assignee: GN Netcom A/S
    Inventors: Finn Jensen, Steve McGugan