Abstract: A phase lock device and method applicable to a data transmission system, particularly to a high speed transmission system are provided. Based on that the optimum operation margin for delaying data strobe is to shift the edge of data strobe to the middle region of data signal, the phase lock device and method suggest a solution, by analyzing the influence of environmental and operational conditions on delaying data strobe and system clock, to adapt delay element to the variation of environmental and operational conditions, so that the delay of data strobe is always in such a range that the data receiver can be enabled to do accurate and reliable data reading, regardless of external interference.