Patents Represented by Attorney Michael Ciraolo

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  • Piperazine derivatives as inhibitors of stearoyl-CoA desaturase
    Patent number: 8039463
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: October 18, 2011
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Kumar Sundaresan, Sandeep N. Raikar, Srinivasa Raju Sammeta, Ganesh Prabhu, Hosahalli Subramanya, Alexander Bischoff
  • Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion
    Patent number: 7569605
    Abstract: The present invention relates to a method of treating a central nervous system disorder, such as a mood disorder (e.g., major depressive disorder) or an anxiety disorder (e.g., general anxiety disorder, social anxiety disorder, post traumatic stress disorder, and panic disorder) with a low dose combination of escitalopram and bupropion.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: August 4, 2009
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Jeffrey Jonas, Anjana Bose, Joyce Tsai
  • Substituted imidazo(1,2-A)pyrimidines and imidazo(1,2-A) pyridines as cannabinoid receptor ligands
    Patent number: 7563797
    Abstract: The present invention relates to compounds of formula I, II, III or IV: wherein R1-R4, R7-R10, R13-R17 and R20-R24 are as described herein. The compounds are active as cannabinoid receptor ligands, e.g., CB2 ligands. Methods of preparing the compounds, compositions containing the compounds and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: July 21, 2009
    Assignee: Forest Laboratories Holding Limited
    Inventors: Gian-Luca Araldi, Matthew Ronsheim, Nhut K. Diep
  • Synthesis of heterocyclic compounds
    Patent number: 7511150
    Abstract: Methods for the synthesis of heterocyclic compounds including N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: March 31, 2009
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Gian-Luca Araldi, Melanie Ronsheim, Nhut Diep, Shao Hong Zhou
  • Pyridoimidazole derivatives
    Patent number: 7501438
    Abstract: The present invention relates to pyridoimidazole derivatives that act as cannabinoid receptor ligands, e.g., CB2 ligands. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: March 10, 2009
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Matthew Ronsheim, Gian-Luca Araldi