Abstract: Compounds of formula (I) in free or salt or solvate form, where T1, T2, Ra and Rb have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Type:
Grant
Filed:
July 12, 2007
Date of Patent:
August 2, 2011
Assignee:
Novartis AG
Inventors:
Catherine Leblanc, Maude Nadine Pierrette Pipet, Robin Alec Fairhurst, Claire Adcock, Robert Alexander Pulz, Duncan Shaw, Nikolaus Johannes Stiefl
Abstract: Systems, methods and apparatus are provided through which an apparatus located on an airfield provides information to pilots in aircraft on the ground and simultaneously gathers information on the motion and position of the aircraft for controllers.
Type:
Grant
Filed:
September 18, 2006
Date of Patent:
March 15, 2011
Assignee:
The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
Abstract: Systems, methods and apparatus are provided through which, in one aspect, one or more wholes and parts of wholes are searched in a database, presented to a user, sold and/or distributed.
Abstract: Systems, methods and apparatus are provided through which in some embodiments a magnetic resonance imaging (MRI) system includes one or more magnetic shield coils positioned asymmetrically in the casing and also positioned in close proximity to one of two apertures of an inner bore of the MRI system. In those embodiments, the position of the one or more magnetic shield coils provides an asymmetric magnetic stray field during operation of the MRI system, which in turn allows operation of electronic medical diagnostic equipment or electronic medical monitoring equipment in close proximity to the MRI.
Type:
Grant
Filed:
March 1, 2005
Date of Patent:
December 16, 2008
Assignee:
General Electric Company
Inventors:
Timothy John Havens, Stephen R. Elgin, Ricardo Becerra
Abstract: Systems, methods and apparatus are provided through which in one aspect, a three-dimensional (3D) image of an object is constructed from a plurality of two-dimensional (2D) images of the object using a specialized filter. The specialized filter implements a linear ramp function, a windowing function, and/or a polynomial function. The 3D image is back-projected from the filtered two-dimensional images, yielding a 3D image that has improved visual distinction of overlapping anatomic structures and reduced blurring.
Type:
Grant
Filed:
June 1, 2004
Date of Patent:
December 18, 2007
Assignee:
General Electric Co.
Inventors:
Baojun Li, Steven W. Metz, John Michael Sabol, Gopal B. Avinash, Jiang Hsieh
Abstract: A drive system for a patient support table in a medical imaging apparatus is provided. In some embodiments, the system comprises at least one first drive means for driving a patient support surface in at least one first direction, at least one second drive means for driving the patient support surface in at least one second direction, wherein the at least first drive means and the at least second drive means are mounted on at least one common mounting member.
Abstract: Apparatus and methods are provided through which a radio-frequency dielectric heater has a cylindrical form factor, a variable thermal energy deposition through variations in geometry and composition of a dielectric, and/or has a thermally isolated power input.
Type:
Grant
Filed:
June 16, 2003
Date of Patent:
October 5, 2004
Assignee:
The United States of America as represented by the
Administrator of the National Aeronautics and Space
Administration
Inventors:
William Herbert Sims, III, Thomas J. Godfroy, Leo Bitteker
Abstract: A disk drive includes an actuator with a shaft and a base with a sleeve that receives the shaft and includes as least one bearing. The shaft extends into the sleeve and through the bearing where it supports the actuator and allows it to pivot in response to electro-magnetic forces. The shaft defines at least one opening for aligning a main body of the actuator together with the shaft and facilitating attachment of the two in proper and secure alignment.