Abstract: Deep computing techniques are employed to mine statistical data bases and patient specific data files contributed from multiple sources, including implantable medical devices (IMDs) and external medical devices and other sources, to formulate patient-specific monitoring, diagnostic, therapeutic and educational information and to deliver the patient-specific diagnostic, therapeutic and educational information to the patient and/or patient health care provider. The present invention advantageously provides patient-specific information for IMD bearing patients that draws upon worldwide expertise and knowledge of IMDs of the type implanted, the patient's disease etiology, the drugs prescribed to the patient, the knowledge of experts in the field, and the optimal modes of operating the IMD to monitor physiologic conditions or apply therapies as reported by experts and medical device manufacturers.

Abstract: A steerable guidewire or stylet that has increased torsional strength is disclosed. A braided structure located in the vicinity of at least the distal end of the guidewire or stylet provides for a more efficient transfer of rotational force over the length of the guidewire or stylet. The braided structure may be comprised of a flat metal ribbon wire that may optionally be reinforced with a polyimide. According to one aspect of the invention, the stylet includes an outer member, and a pull-wire located within the outer member. The pull-wire is coupled to the distal tip of the outer member such that when tension is applied to the pull-wire, the distal tip of the outer member is deflected. The distal tip of the outer member may be formed of a material having superelastic properties such as a nickel titanium alloy, whereas the proximal portion of the stylet may be formed of a material having more torsional strength.