Patents Represented by Attorney Michael G. Williams
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Patent number: 8197775Abstract: The present invention provides a detection article including at least one fluid control film layer having at least one microstructured major surface with a plurality of microchannels therein. The microchannels are configured for uninterrupted fluid flow of a fluid sample throughout the article. The film layer includes an acquisition zone for drawing the fluid sample into the plurality of microchannels at least by spontaneous fluid transport. The film layer also includes a detection zone having at least one detection element that facilitates detection of a characteristic of the fluid sample within at least one microchannel of the detection zone. The detection article may be formed from a plurality of film layers that are stacked to form a three-dimensional article.Type: GrantFiled: May 22, 2007Date of Patent: June 12, 2012Assignee: 3M Innovative Properties CompanyInventors: Raymond P. Johnston, Patrick R. Fleming, Koichi Sano
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Patent number: 8097471Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group of process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.Type: GrantFiled: November 10, 2010Date of Patent: January 17, 2012Assignee: 3M Innovative Properties CompanyInventors: William Bedingham, James E. Aysta, Barry W. Robole, Kenneth B. Wood
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Patent number: 8012427Abstract: An apparatus assembly for detecting an analyte in a sample of material includes a valve, a frame, and a plurality of housing segments. The valve may be actuated to adjust a flow path and flow rate through the housing segments.Type: GrantFiled: August 2, 2006Date of Patent: September 6, 2011Assignee: 3M Innovative Properties CompanyInventors: G. Marco Bommarito, Larry H. Dodge, Brinda B. Lakshmi, Triet M. Lu, Jeffrey D. Smith
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Patent number: 7957575Abstract: The invention is directed to counting techniques for counting biological agents on a biological growth plate or similar medium. In order to automate the counting of biological agents, a biological growth plate is inserted into a biological scanning unit. Upon insertion of the biological growth plate, the biological scanning unit generates an image of the plate. Then, the amount of biological agents that appear in the image, such as a number of bacteria colonies, can be counted or otherwise determined using image processing and analysis routines performed either by the scanning unit or an external computing device, such as a desktop computer, workstation or the like. A variety of counting rules are described herein that can be used to improve the accuracy of automated counts of biological agents on a biological growth plate.Type: GrantFiled: June 8, 2010Date of Patent: June 7, 2011Assignee: 3M Innovative Properties CompanyInventors: Michael R. Plumb, Christine A. Binsfeld, Doyle T. Potter
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Patent number: 7910790Abstract: The present invention provides medical articles having a fluid control film component which comprise a sheet having microchannels that permit directional flow of a liquid. Articles incorporating the fluid control film include: wound dressings, wound drains, tympanostomy fluid wicks, intravenous access site dressings, drug delivery dressings, and sweat collection patches.Type: GrantFiled: August 23, 2010Date of Patent: March 22, 2011Assignee: 3M Innovative Properties CompanyInventors: Raymond P. Johnston, Matthew T. Scholz, Steven B. Heinecke, Charles A. Hentzen
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Patent number: 7781639Abstract: The present invention provides medical articles having a fluid control film component which comprise a sheet having microchannels that permit directional flow of a liquid. Articles incorporating the fluid control film include: wound dressings, wound drains, tympanostomy fluid wicks, intravenous access site dressings, drug delivery dressings, and sweat collection patches.Type: GrantFiled: January 14, 2002Date of Patent: August 24, 2010Assignee: 3M Innovative Properties CompanyInventors: Raymond P. Johnston, Matthew T. Scholz, Steven B. Heinecke, Charles A. Hentzen
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Patent number: 7771986Abstract: A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines means for protecting the binding partner from being dislodged or scraped off the solid support by physical means. The provision of protection against the binding partner being dislodged from or scraped off the solid support improves the reliability of tests such as immunoassays being conducted with the solid support and also enables such tests to be automated. Modules and machines for use with the solid support, and the automated conduct of tests are also disclosed.Type: GrantFiled: June 27, 2007Date of Patent: August 10, 2010Assignee: 3M Innovative Properties CompanyInventors: Megan Ash, David William Edwards, Aaron Peter Gibbeson, Dianne Barbara Kerr, Lisa Frances Moncur, Philip Albert Myers
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Patent number: 7738689Abstract: The invention is directed to counting techniques for counting biological agents on a biological growth plate or similar medium. In order to automate the counting of biological agents, a biological growth plate is inserted into a biological scanning unit. Upon insertion of the biological growth plate, the biological scanning unit generates an image of the plate. Then, the amount of biological agents that appear in the image, such as a number of bacteria colonies, can be counted or otherwise determined using image processing and analysis routines performed either by the scanning unit or an external computing device, such as a desktop computer, workstation or the like. A variety of counting rules are described herein that can be used to improve the accuracy of automated counts of biological agents on a biological growth plate.Type: GrantFiled: September 13, 2007Date of Patent: June 15, 2010Assignee: 3M Innovative Properties CompanyInventors: Michael R. Plumb, Christine A. Binsfeld, Doyle T. Potter
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Patent number: 7496225Abstract: The invention is directed to a biological scanner for scanning biological growth plates. The biological growth plate is loaded into the biological scanner via motorized rollers, and an actuator presses the growth plate against a platen once the growth plate is drawn to a scanning position within the scanner. The biological scanner then generates one or more images of the growth plate. Moreover, sensors can be arranged to facilitate sensing and positioning of the growth plate in a plurality of locations for imaging different parts of the plate. Additional embodiments are directed to features such as a hinged door that facilitates access to the scanner, and footings disposed on various sides of the scanner to facilitate flip-over of the scanner for simplified use by right-handed or left-handed users.Type: GrantFiled: September 4, 2003Date of Patent: February 24, 2009Assignee: 3M Innovative Properties CompanyInventors: Josef A. Graessle, Kevin R. Green, Albert Vent
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Patent number: 7488807Abstract: Monoclonal antibodies, and antigen binding fragments thereof, which bind to Protein A of Staphylococcus aureus are provided.Type: GrantFiled: November 22, 2006Date of Patent: February 10, 2009Assignee: 3M Innovative Properties CompanyInventors: Patrick A. Mach, Mara S. Reif-Wenner