Patents Represented by Attorney, Agent or Law Firm Michael Gollin
  • Substituted 2-pyrrolidinone activators of PKC
    Patent number: 6284784
    Abstract: Compounds of formula I: wherein R1 and R2 have any of the values defined in the specification, and their pharmaceutically acceptable salts, are PKC activators and are useful for treating diseases, such as, for example, cancer. Also disclosed are pharmaceutical compositions comprising compounds of formula I, processes for preparing compounds of formula I, and intermediates useful for preparing compounds of formula I.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: September 4, 2001
    Assignee: Georgetown University
    Inventors: Alan P. Kozikowski, Shaomeng Wang, Lixin Qiao