Patents Represented by Attorney, Agent or Law Firm Michael P. Dougherty
  • Mutant penicillin G acylases
    Patent number: 6403356
    Abstract: New mutant penicillin G acylases preferably from E. coli are provided, exhibiting altered enzymatic activity. These penicillin G acylases are obtained by expression of a gene encoding said penicillin G acylase having an amino acid sequence which differs at least in one amino acid from the wild-type penicillin G acylase.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: June 11, 2002
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Li You, John James Usher, Brenda Joyce White, Jiri Novotny