Abstract: Methionine.sup.5 -enkephalin sulfoxides and sulfones having agonist activity at opiate receptors are disclosed herein. These sulfoxides and sulfones are useful as analgesics, non-addicting narcotic antagonists and anti-diarrheal agents.
Type:
Grant
Filed:
May 7, 1976
Date of Patent:
March 13, 1979
Assignee:
G. D. Searle & Co.
Inventors:
David A. Jones, Jr., James M. Schlatter