Abstract: The present invention relates to ink-jet ink compositions that comprise modified pigment particles (macromolecular chromophores) having functional groups covalently attached for water solubility and reactive moieties covalently attached to the pigments. MMC with such reactive moieties attached can either a) react directly with cellulose or other textile material or, b) can participate in polymerization reactions. These reactive moieties may in turn be further derivatized to provide the desirable attribute, such as enhanced smearfastness, enhanced print quality, improved bleed control, and improved resistance to water when applied to the media. Moreover, inks formulated with these reactive MMCs demonstrate viscosity and surface tension characteristics that are useful in ink-jet printing. This includes thermal ink jet, piezoelectric ink jet, and continuous ink jet printing.