Patents Represented by Attorney Michelle Lewis
  • Patent number: 7262025
    Abstract: An expression vector capable of expressing high levels of heterologous proteins having a cytomegalovirus (CMV) enhancer 5? upstream from a myeloproliferative sarcoma virus (MPSV) promoter.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: August 28, 2007
    Assignee: ZymoGenetics, Inc.
    Inventor: Margaret Dow Moore
  • Patent number: 7247608
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zFGF-5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells and may be used for remodelling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF-5 polypeptides.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: July 24, 2007
    Assignee: ZymoGenetics, Inc.
    Inventors: Theresa A. Deisher, Darrell C. Conklin, Fenella Raymond, Thomas R. Bukowski, Susan D. Holderman, Birgit Hansen, Paul O. Sheppard
  • Patent number: 7135459
    Abstract: The present invention relates to methods of using zFGF5 compositions to proliferate chondrocytes and their progenitors, and to induce deposition of cartilage. zFGF5 compositions are disclosed for treating disorders associated with chondrocytes, such as cartilage injuries and defects. In addition, methods for treating neurological disorders, such as stroke, are disclosed, and methods for using zFGF5 compositions to stimulate growth of cells associated with neurological injury and disease are disclosed.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: November 14, 2006
    Assignee: ZymoGenetics, Inc.
    Inventors: Theresa A. Deisher, Darrell C. Conklin