Patents Represented by Attorney Millen, White, Zelano & Branican
  • Patent number: 7754904
    Abstract: A process is described in which an unsaturated fat is reacted in a homometathesis reaction in the presence of at least one non-aqueous ionic liquid to produce both an olefinic fraction and a composition of monoalcohol diesters or diacids. Particular application to a mixture of esters of an oleic sunflower seed oil or an oleic rapeseed oil, the process producing both an olefinic fraction and a composition of monoalcohol diesters or diacids wherein, in general, more than half of its chains is constituted by unsaturated C18 chains.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: July 13, 2010
    Assignee: Institut Francais du Petrole
    Inventors: Hélène Olivier-Bourbigou, Gérard Hillion, Christophe Vallee
  • Patent number: 7307100
    Abstract: Novel compounds of the formula I in which R, X, n and m are as defined herein are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: December 11, 2007
    Assignee: Merck Patent GmbH
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Patent number: 7145004
    Abstract: The present invention relates to a process for the preparation of monohydroperfluoroalkanes, bis(perfluoroalkyl)phosphinates and perfluoroalkylphosphonates which comprises at least the treatment of at least one perfluoroalkylphosphorane with at least one base in a suitable reaction medium.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: December 5, 2006
    Assignee: Merck Patent Gesellschaft
    Inventors: Nikolai Ignatyev, Michael Weiden, Urs Welz-Biermann, Udo Heider, Peter Sartori, Andriy Kucheryna, Helge Willner
  • Patent number: 6156737
    Abstract: The present invention is directed to a method of treating hepatitis B viral infections in mammals comprising the administration of .beta.-L-5-fluoro-2',3'-dideoxycytidine and pharmaceutically acceptable derivatives thereof.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: December 5, 2000
    Assignee: BioChem Pharma Inc.
    Inventors: Tarek Mansour, Allan H.L. Tse
  • Patent number: 5998646
    Abstract: These compounds are denoted by the formula (I): ##STR1## in which R denotes a tert-butyl, tert-amyl or 2-ethylhexyl radical. To prepare them, methacrylic acid is reacted with a tetraalkoxytitanium Ti(OR).sub.4, where R=isopropyl or tert-butyl, to obtain a corresponding compound (I), or with Ti(OR) (OtAm).sub.3, where R=isopropyl or tert-butyl and tAm=tert-amyl, to obtain a compound (I) with R=tert-amyl, the compounds (I) with R=isopropyl or tert-butyl furthermore denoting intermediate synthesis products which can be reacted with tert-amyl alcohol or with 2-ethylhexanol, to obtain a compound (I) in which R denotes tert-amyl or 2-ethylhexyl respectively.
    Type: Grant
    Filed: November 4, 1998
    Date of Patent: December 7, 1999
    Assignee: Elf Atochem S.A.
    Inventors: Alain Riondel, Michel Camail, Andre Margaillan, Jean-Louis Vernet, Marie Humbert
  • Patent number: 5231219
    Abstract: Process for the manufacture of .alpha.-fluoroacrylates of general formula: ##STR1## with R' alkyl, aryl or cycloalkyl, according to which source of formalin, consisting of paraformaldehyde is reacted with an .alpha.-fluorophosphonoacetate in aqueous medium in the presence of a salt of a weak inorganic acid.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: July 27, 1993
    Assignee: Elf Atochem S.A.
    Inventors: Claude Grison, Nathalie Boulliung, Philippe Coutrot