Abstract: The subject invention involves process for making fuctionalized oxazolidinones having structure (1) wherein: (a) R1 and R2 are each independently selected from hydrogen, alkyl, aryl and heterocycle, or R1 and R2 are attached to form a cycloalkyl, aryl or heterocyclic ring; (b) R3 is selected from primary and secondary alkly (—R6), —SO2—R4, and —C(O)NH—R5; (c) R4 is aryl; and (d) R5 is alkyl or aryl; the process comprising a reaction step carried out in a reaction mixture, wherein an oxazolidinone is reacted with an electrophile selected from R6-Br, R6-I, R4-SO2Cl, and R5-NCO; the reaction mixture comprising a non-protic and non-oxidizing solvent and potassium fluoride on alumina; and without the presence of a substantial amount of a strong base in the reaction mixture. The subject invention also involves libraries of functionalized oxazolidinone compounds and their preparation using such processes.

Abstract: The subject invention involves chess pieces made primarily from hardware components and chess sets of such chess pieces. Each chess piece comprises a center shaft component comprising a vertical threaded rod having a bottom end, a top end, and a surface from the rod's bottom end to its top end that is partially or wholly cylindrical and threaded. The center shaft component optionally comprises a head at either its bottom or top end. Each chess piece also comprises holed components, each holed component having a hole through which or into which the center shaft component projects. The holed components are stacked along the length of the center shaft component. All the holed components are secured in place by one or more holed components which are nuts having threads complementary to those of the threaded rod, and optionally by the head of the center shaft component.

Abstract: The subject invention involves processes for making 1-aminohydantoin compounds using a solid support resin, comprising the following steps; (a) preparing a resin-bound protected &agr;-hydrazinyl ester; (1) by reacting the resin with an &agr;-bromo carboxylic acid, then with a protected hydrazine; or (2) by reacting the resin with a protected &agr;-hydrazinyl carboxylic acid; (b) preparing a resin-bound imine by removing the blocking group from the hydrazinyl moiety, then reacting the unprotected hydrazinyl moiety with an aldehyde or ketone; (c) preparing a resin-bound secondary urea: (1) by reacting the imine with p-nitrophenylchloroformate or trisphosgene, then with a primary amine; or (2) by reacting the imine with an isocyanate, and (d) preparing the 1-aminohydantoin compound by removing the secondary urea from the resin and cyclizing it.

Abstract: Compounds having the general structure: which are effective antimicrobial agents.

Abstract: The subject invention involves compounds having the structure: wherein the C.sub..alpha. --N.sub..beta. and C.sub.5 -C.sub.6 bonds are independently single or double bonds, R1 is selected from alkyl, aryl, and heterocycle; R2-R13 are independently selected from hydrogen and other substituents; and pharmaceutically-acceptable salts thereof. The subject invention also involves pharmaceutical compositions containing such compounds, and methods for treating or preventing diseases and disorders using such compounds.

Abstract: The present invention provides a firm, mild, good performing, low-smear semi-solid or solid dishwashing product. The rheology of the dishwashing product is such that structural elements have been separated from functional elements to obtain best structure properties and in-use properties. By using an interlocking mesh of carboxylic acid and/or neutralized carboxylic acid fibers and/or platelets to provide a support structure, the semi-solid or solid dishwashing product can be loaded with superior performing dishcare materials (e.g., mild surfactants) and appearance enhancers without dependence on surfactant-water phase behavior to provide the support structure. As a result, the present dishwashing product is milder than semi-solid dishwashing products currently on the market. The support structure of the present product, and preferably the use of hygroscopic surfactants, provide a product with lower smear than current gel dishwashing products.

Abstract: The performance of photobleaches such as the zinc phthalocyanines is enhanced by means of alkylene amino/carboxylate or alkylene amino/phosphonate chelants. Thus, sulfonated zinc phthalocyanine plus diethylenetriamine pentaacetate provide enhanced photobleaching of laundered fabrics. Detergent compositions comprising the improved photobleach systems are provided.

Abstract: Disclosed are compositions of laundry detergent bars that do not develop undesirable brittleness during storage. The disclosed compositions comprise alkyl sulfate surfactant, preferably coconut alkyl sulfate, and polyethylene glycol. The polyethylene glycol prevents the development of undesirable brittleness in such alkyl sulfate-containing laundry bars.

Abstract: The subject invention involves laundry bar compositions comprising:(a) from about 20% to about 70% surfactant, the surfactant consisting essentially of from about 50% to 100% soap and from 0% to about 50% alkylbenzene sulfonate;(b) from about 12% to about 24% water;(c) from about 61/4% to about 20% calculated excess alkali metal carbonate;(d) from about 2% to about 20% water-soluble inorganic strong-electrolyte salt;(e) from 0% to about 4% whole-cut starch;(f) from 0% to about 8% added alkali metal bicarbonate;(g) from 0% to about 30% phosphate builder;(h) from 0% to about 40% insoluble filler; and(j) from 0% to about 15% other ingredients selected from other builders, chelants, enzymes, soil release polymers, dye transfer inhibiting agents, fabric softeners, bleaching agents, gums, thickeners, binding agents, other starches, soil suspending agents, optical brighteners, colorants and opacifiers, perfumes, bluing agents, and mixtures thereof;the bar having a firmness measurement of at least about 10 kg.

Abstract: This invention involves involves the use of compounds having the following structure: ##STR1## wherein: (a) R is unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; and(b) R' is selected from hydrogen; unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; unsubstituted C.sub.1 -C.sub.3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo;for preventing or treating of disorders modulated by alpha-2 adrenoceptors.The subject invention also involves novel compounds and compositions.

Abstract: The subject invention relates to compounds having the structure: ##STR1## wherein (a) n is an integer from 1 to about 3;(b) X and Y are each independently selected from O, S and CH.sub.2, with at least one of X and Y being O or S;(c) R is unsubstituted, straight or branched chain alkanyl or alkanoxy having from 1 to about 3 non-hydrogen atoms; and(d) R' is selected from hydrogen, methyl, cyano, and halo; pharmaceutical compositions containing such compounds; and the use of such compounds for preventing or treating of disorders modulated by alpha-2 adrenoceptors.

Abstract: The subject invention relates to compounds having the structure: ##STR1## as defined in the claims, and to pharmaceutical compositions containing such compounds, and the use of such compounds for preventing or treating of disorders modulated by alpha-2 adrenoceptors.

Abstract: The subject invention involves processes for making granular compositions comprising soil release polymers, the polymers comprising at least about 10% of substantially linear esters having a backbone; the esters being uncapped or end-capped on one or both ends of the backbone; the esters comprising in their backbones oxyalkyleneoxy units and hydrophobic aryldicarbonyl units; the esters having a molecular weight of from about 500 to about 20,000; the polymers if in solid state having the tendency when exposed to moisture to spontaneously rearrange from an amorphous form which is readily soluble in water to a crystalline form which is relatively insoluble in water; the process comprising the following steps:a) taking the soil release polymers, in which are dispersed from 0% to about 25% alkylaryl or alkyl sulfonate crystallization-reducing stabilizers, in molten state at a temperature of at least about 180.degree. C.

Abstract: The subject invention involves laundry compositions comprising:(a) from about 10% to about 35%, anionic surfactant,(b) at least about 0.5% polyethylene glycol,(c) at least about 5% water, and(d) at least about 5% phosphate builder; the composition being in the form of a bar; and processes for making such bars.

Abstract: The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: ##STR1## wherein: (a) R is unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; and(b) R' is selected from hydrogen; unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; unsubstituted C.sub.1 -C.sub.3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo.The subject invention also involves the use of such compounds for preventing or treating other respiratory, ocular and/or gastrointestinal disorders. The subject invention also involves novel compounds having the above structure wherein R' is hydrogen or fluoro or cyano.

Abstract: The subject invention involves processes for making granular compositions comprising soil release polymers, the polymers comprising at least about 10% of substantially linear esters having a backbone; the esters being uncapped or end-capped on one or both ends of the backbone; the esters comprising in their backbones oxyalkyleneoxy units and hydrophobic aryldicarbonyl units; the esters having a molecular weight of from about 500 to about 20,000; the polymers if in solid state having the tendency when exposed to moisture to spontaneously rearrange from an amorphous form which is readily soluble in water to a crystalline form which is relatively insoluble in water; the process comprising the following steps:a) taking the soil release polymers, in which are dispersed from 0% to about 25% alkylaryl or alkyl sulfonate crystallization-reducing stabilizers, in molten state at a temperature of at least about 180.degree. C.

Abstract: The subject invention relates to compounds having the structure: ##STR1## wherein (a) n is an integer from 1 to about 3;(b) X and Y are each independently selected from O, S and CH.sub.2, with at least one of X and Y being O or S;(c) R is unsubstituted, straight or branched chain alkanyl or alkanoxy having from 1 to about 3 non-hydrogen atoms; and(d) R' is selected from hydrogen, methyl, cyano, and halo; pharmaceutical compositions containing such compounds; and the use of such compounds for preventing or treating one or more of respiratory disorders, ocular disorders, and gastrointestinal disorders.

Abstract: The present invention relates to a detergent composition comprising a gel wholly or predominantly in hexagonal liquid crystal phase, said gel comprising:(a) from about 15% to about 50% ethoxylated alkyl sulfate surfactant by weight of the gel, wherein the alkyl group of the ethoxylated alkyl sulfate surfactant has an average from about 8 to about 20 carbon atoms, and wherein the ethoxylated alkyl sulfate surfactant has an average degree of ethoxylation from about 0.5 to about 15;(b) from about 1% to about 20%, by weight of the gel, secondary sulfonate surfactant selected from the group consisting of alkylbenzene sulfonates, alkyltoluene sulfonates, paraffin sulfonates, olefin sulfonates, alpha-sulfonated fatty acid alkyl esters, and mixtures thereof;(c) optionally from 0% to about 15% other surfactants by weight of the gel;(d) from about 40% to about 80% water by weight of the gel;(e) from about 0.

Abstract: The subject invention encompasses methods and compositions comprising phosphate derivatives of triclosan for treating or preventing dental plaque, gingivitis or periodontal disease, of the oral cavity in humans or lower animals.

Abstract: A continuous process for producing high active, high density detergent granules consists essentially of the following steps:(a) preparing a mixture in a high-speed mixer, the mixture being prepared from components fed to the mixer consisting essentially of the following:(1) from about 15% to about 35% anionic surfactant acid selected from alkylbenzene sulfonic acid and alkyl sulfuric acid and mixtures thereof;(2) from about 5% to about 65% phosphate builder selected from polyphosphates and pyrophosphates and mixtures thereof; and(3) from about 10% to about 65% particulate carbonate selected from sodium carbonate and potassium carbonate and mixtures thereof, the amount of carbonate being at least about 2 times the amount theoretically needed to neutralize the anionic surfactant acid;(b) agglomerating the mixture from step (a) in a moderate-speed mixer; whereby the anionic surfactant acid is neutralized by the carbonate, and the resulting detergent granules have a bulk density of greater than about 550 g/l and