Abstract: The invention provides methods for conducting cancer immunotherapy and diagnosis using cytochrome P450 1B1 and peptide fragments thereof.

Abstract: Fenofibrate microparticles are prepared using a combination of surface modifiers with a phospholipid. Particle size growth and stability are controlled while significantly smaller sized fenofibrate particles are produced.

Abstract: The invention provides diagnostic procedures wherein the presence or absence of a cell-proliferating disorder, e.g., a breast cancer, may be determined. The imaging agents of the invention include alpha-fetoprotein hydrophilic analogs which have been determined to target cancers, e.g., breast cancer, and are also anti-cell proliferating in nature. These modulators contain amino acid structures which are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide; a peptidomimetic; or may be in the form of a pharmaceutically acceptable scaffold, such as a polycyclic hydrocarbon to which is attached the necessary amino acid structures. The imaging agents of the invention further comprise an imaging moiety that allows for the imaging of the area targeted by the imaging agent.

Abstract: The invention relates to a combined AC-DC to DC converter. The converter provides the option of coupling to an AC supply source with at least one phase and the further option of coupling to at least one DC supply source. The converter obtains supply from at least one supply source at a time; and the converter contains controllable contact means that are, upon switching between supply sources, capable of connecting and disconnecting the individual supply sources to/from the converter; whereby a pulse signal is generated. The converter contains at least one coil that is in connection with at least one DC output.

Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.

Abstract: The invention features an immunogenic composition containing a frequently-recognized epitope of an HIV-1 accessory protein such as Vpr and methods of inducing an immune response using such an epitope. The epitope peptide contains the amino acid sequence ALIRILQQL of a functionally active domain or a structural domain of the accessory protein.

Abstract: The present invention relates to systems and methods for controlling head pressure in a vapor compression system, e.g. in a precision air conditioning system. One embodiment of the invention provides a method for regulating working fluid flow in a vapor compression system including a compressor. The method includes: providing a controller; receiving signals at the controller representative of a monitored discharge pressure in a discharge line of the compressor; and using the controller to provide a control signal to an actuator that controls a flow control valve that, in turn, controls working fluid flow into the system, the control signal being responsive at least in part to a difference between a set point pressure and the monitored discharge pressure.

Abstract: An uninterruptible power supply that provides power to an electrical device, the uninterruptible power supply that includes a first housing; a cover plate that includes a plurality of electrical outlets located on a surface of the cover plate and said cover plate is connected to the first housing in an angled position; and a battery in electrical communication with the plurality of electrical outlets on the surface of the cover plate, and the battery being removably attached to the first housing.

Abstract: A motor assisted swivel is disclosed which aids in proper rotation of a swivel in a tether system for animal testing. The swivel may have any number of fluid conduits or electrical or optical leads. A switching mechanism determines a direction of rotation of the tether and activates a motor to rotate the swivel in the direction of rotation. When rotation of the tether stops, further rotation of the swivel causes the switching mechanism to deactivate the motor. The switching mechanism may include a hinged connector with magnets on each side and reed switches to sense movement of the connector about its hinge.

Abstract: A gas distribution unit for use in a rack, that holds rack-mounted equipment that produces heat during operation, includes a housing defining a cavity, an exhaust port in a top wall of the housing, and at least one intake port configured to provide fluid communication between the cavity and a volume of gas external to the housing, the at least one intake port being at least partially laterally displaced relative to the exhaust port, the housing being configured to be disposed in and coupled to the rack and to direct gas from the cavity substantially directly upward through the exhaust port when coupled to the rack, and at least one fan coupled to and disposed within the housing and configured to draw gas through the at least one intake port, and to force the drawn-in gas out of the gas distribution unit through the exhaust port.

Abstract: The invention provides techniques for compensating for current leakage from a loop filter during off times of a PLL between on times of the PLL, e.g., when a cell phone is in paging mode. The leakage current is compensated by providing offsetting charge to ensure that the VCO tuning voltage when the PLL is turned from “off” to “on” is at or near the VCO tuning voltage when the PLL is locked (the VCO-lock voltage). Several techniques can be used compensate for the leakage current and several techniques can be used to determine how accurately the leakage current is being compensated for, and what, if any, adjustments to make in the offsetting charge to adequately compensate for the leakage current.

Abstract: Composition containing a lactic acid-producing bacterial strain, e.g., Bacillus coagulans for inhibition of pathogenic bacterial infections. Spores or extracellular products produced by the bacterial strains are also useful as inhibitory agents.

Abstract: A method of imaging using magnetic resonance includes administering hyperpolarized noble gas to a subject in a region to be imaged, applying a magnetic field of a magnitude between about 0.0001 Tesla and about 0.1 Tesla to the subject at least in the region of the subject to be imaged, detecting a spatial distribution of magnetic resonance signals of the hyperpolarized noble gas in the subject, and producing a representation of the spatial distribution.

Abstract: Interleukin-18 binding proteins which are capable of binding IL-18 and/or modulating and/or blocking IL-18 activity are provided. Methods for their isolation and recombinant production, DNAs encoding them, DNA vectors expressing them, vectors useful for their expression in humans and other mammals, antibodies against them are also provided.

Abstract: Novel angiogenesis/anti-angiogenesis secreted proteins and the nucleic acid sequences which encode them are disclosed by the present invention.

Abstract: Aortic-preferentially-expressed gene-1 (APEG-1) and striated muscle preferentially expressed (SPEG) polypeptide, DNA sequences encoding and controlling the transcription of the APEG-1/SPEG encoding gene, methods of diagnosing vascular injury, methods of conferring smooth muscle-cell specific expression, and methods of inhibiting vascular smooth muscle cell proliferation by increasing the level of APEG-1 at the site of vascular injury.