Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Grant
Filed:
January 11, 2002
Date of Patent:
January 31, 2006
Assignee:
Curagen Corporation
Inventors:
Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong
Abstract: The invention provides biological molecules modified by reaction with a compound having the formula: R1—X—R2, wherein R1 is a cyclic ether group or an amino group, R2 is an alkoxysilane group and X is a moiety chemically suitable for linking the cyclic ether group or the amino group to the alkoxysilane group. The invention also provides arrays, or “biochips,” comprising these modified biological molecules. Also provided are methods for making and using these compositions.
Type:
Grant
Filed:
May 10, 2001
Date of Patent:
December 27, 2005
Assignees:
Baylor College of Medicine, Spectral Genomics, Inc.
Inventors:
Allan Bradley, Wei-Wen Cai, Upendra Marathi
Abstract: Embodiments of the invention provide techniques for calibrating voltage-controlled oscillators (VCOs). Multiple VCOs may be disposed on a chip with the VCOs having different frequency ranges. The VCOs may be selected and tested to determine a desired VCO to use to tune to a selected channel frequency. Each of the VCOs has multiple possible varactor configurations. The varactor configurations of the desired VCO determined to be used to tune to the selected channel frequency can be selected and tested to determine a desired varactor configuration for the desired VCO. The desired VCO with the desired varactor configuration will preferably be able to produce a full range of desired frequencies corresponding to all channel frequencies desired.
Type:
Grant
Filed:
November 13, 2003
Date of Patent:
August 23, 2005
Assignee:
Skyworks Solutions, Inc.
Inventors:
Alyosha C. Molnar, Rahul Magoon, Madhukar Reddy, Jackie Cheng