Patents Represented by Attorney, Agent or Law Firm Monsanto Company
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Patent number: 7202085Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.Type: GrantFiled: June 3, 2005Date of Patent: April 10, 2007Assignee: Calgene LLCInventors: Tim N. Oulmassov, Kevin E. McBride, Paula C. Miller, John C. Anderson, Lyle D. Crossland, Thomas H. Adams, Barbara A. Qurollo, Victoria Gavrias
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Patent number: 7078503Abstract: Promoters from male reproductive tissues are isolated from corn. These promoters can be used in plants to regulate transcription of target genes including genes for control of fertility, insect or pathogen tolerance, herbicide tolerance or any gene of interest.Type: GrantFiled: June 28, 2001Date of Patent: July 18, 2006Assignee: Monsanto Technology, LLCInventors: Timothy W. Conner, Patrice Dubois, Marianne Malven, James D. Masucci
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Patent number: 6461997Abstract: New herbicidal compounds are provided having the formula wherein Y is oxygen or sulfur; R1 and R2 are each independently a C1-4 hydrocarbyl group, unsubstituted or substituted with one or more halogen, haloalkyl, hydroxy, alkoxy, carboxy, amido, cyano or amino groups; or R1 and R2, together with the carbamoyl nitrogen atom to which they are attached, form a nitrogen-containing five or six membered ring, the ring being optionally interrupted by an ethereal oxygen atom and unsubstituted or substituted with one or more hydroxy, amido, cyano, amino or C1-8 alkyl, alkenyl, alkynyl, cycloalkyl, arylalkyl, alkoxy, aminoalkyl or haloalkyl groups; and R3 is hydrogen, halogen, or an alkyl, cycloalkyl, alkenyl, cycloalkenyl, cycloalkylalkenyl, aryl, arylalkyl, alkylthio or arylalkylthio group that is unsubstituted or substituted with one or more halo, hydroxy, alkoxy, acetyloxy, benzoyloxy, alkoxycarbonyl, silyl or alkylsilyl groups; or an agronomically acceptable acid addition salt or metal complex ofType: GrantFiled: January 13, 2000Date of Patent: October 8, 2002Assignee: Monsanto Technology LLCInventors: Shridhar G. Hegde, Martin D. Mahoney
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Patent number: 6245758Abstract: The present invention provides a method for the treatment of diseases by the decomposition of peroxynitrite, preferably decomposition to benign products, comprising the use of a complex which is a selected ligand structure providing a complexed metal such as Mn, Fe, Ni and V transition metals. The method of use, as well as novel pharmaceutical compositions therefor, are for the treatment of diseases advantageously affected by decomposition of peroxynitrite ed at a rate over the natural background rate of decay of peroxynitrite in humans suffering from the disease which comprises administration of an amount of a complex, in dosage unit form, which is effective for such acceleration of the decomposition of peroxynitrite .Type: GrantFiled: September 9, 1996Date of Patent: June 12, 2001Inventors: Michael K. Stern, Daniela Salvemini
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Patent number: 6133252Abstract: A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein Z.sub.1 and Z.sub.2 are C or N and are part of an aromatic ring selected from benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole, and isothiazole;A is selected from --C(X)-amine, --C(O)--SR.sub.3, --NH--C(X)R.sub.4, and --C(.dbd.NR.sub.3)--XR.sub.7 ;B is --W.sub.m --Q(R.sub.2).sub.3 or selected from o-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R.sub.4 ;Q is C, Si, Ge, or Sn;W is --C(R.sub.3).sub.p H.sub.(2-p) --; or when Q is C, W is selected from --C(R.sub.3).sub.p H.sub.(2-p) --, --N(R.sub.3).sub.m H.sub.(1-m) --, --S(O).sub.p --, and --O--;X is O or S;n is 0, 1, 2, or 3;m is 0 or 1;p is 0, 1, or 2;each R is independently selected from functional groups disclosed the specification.Type: GrantFiled: November 4, 1998Date of Patent: October 17, 2000Assignee: Monsanto CompanyInventors: Dennis Paul Phillion, Diane Susan Braccolino, Matthew James Graneto, Wendell Gary Phillips, Karey Alan Van Sant, Daniel Mark Walker, Sai Chi Wong
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Patent number: 6018100Abstract: A full-length transcript promoter from figwort mosaic virus (FMV) is identified and its DNA sequence given. The promoter functions as a strong and uniform promoter for chimeric genes inserted into plant cells. This strong promoter function is exhibited by a histochemical assay in floral buds and by reproductive scores of transgenic plants including the promoter. The promoter preferably includes a 5' leader sequence that may be from the FMV itself or from a heterologous source with respect to the promoter. The promoter is used in a plant cassette vector, a chimeric gene and in methods for transforming plant cells to obtain transgenic plants, plant cells or seeds incorporating the FMV promoter.Type: GrantFiled: February 6, 1996Date of Patent: January 25, 2000Assignee: Monsanto CompanyInventor: Stephen Gary Rogers
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Patent number: 5986128Abstract: A method is described for making solution stable salts of iminodiacetic acid (IDA), useful as precursors in the manufacture of N-phosphonomethylglycine. Concentrated dialkali salts of IDA which are insoluble at temperatures below about 55.degree. C., such as the disodium salt (DSIDA) are acidified to monoalkali salts, such as monosodium IDA (MSIDA). The resulting salts are stable in solution, and may conveniently be stored or transported in solution without recourse to dilution, heating, or similar measures.Type: GrantFiled: November 1, 1996Date of Patent: November 16, 1999Assignee: Monsanto CompanyInventor: Lowell Richard Smith
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Patent number: 5976498Abstract: The present invention is directed to complexes represented by the formula: ##STR1## wherein R, R', R.sub.1, R'.sub.1, R.sub.2, R'.sub.2, R.sub.3, R'.sub.3, R.sub.4, R'.sub.4, R.sub.5, R'.sub.5, R.sub.6, R'.sub.6, R.sub.7, R'.sub.7, R.sub.8, R'.sub.8, R.sub.9, R'.sub.9, M, X, Y, Z and n are defined herein for use as contrast agents in diagnostic imaging.Type: GrantFiled: August 16, 1996Date of Patent: November 2, 1999Inventors: William L. Neumann, Dennis P. Riley, Randy H. Weiss, Susan L. Henke, Patrick J. Lennon, Karl W. Aston
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Patent number: 5723049Abstract: A process is provided for selectively converting formaldehyde in an acidic organic waste aqueous stream in the most part to formose sugars rather than to alkali metal formate and methanol by reacting the stream with a strong alkali base to provide a pH of at least about 8.5 and heating the resulting basic solution to a temperature of at least about 80.degree. C. The formaldehyde is present in the waste stream in amounts between about 1000 ppm to 10,000 ppm.Type: GrantFiled: September 23, 1996Date of Patent: March 3, 1998Assignee: Monsanto CompanyInventor: Robert B. Weisenfeld
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Patent number: 5716903Abstract: Solid N-phosphonomethylglycine or glyphosate acid is charged to a substantially closed system and then partially pre-dried as by continuously recirculating it through a hot air grinding/drying system. A cooled solution of ammonium hydroxide is then metered into and reacted with the partially dried glyphosate acid as it is being recirculated in a manner such that the moisture content of the reaction mass so formed is continuously decreased throughout the reaction. Following completion of the ammonium hydroxide addition, a powdered reaction mass/product having a moisture content of about 2 wt. % is formed. Significantly, at this stage, the ammonium glyphosate product is suitable for end use and it can be readily dissolved in water and immediately used as a herbicide or plant growth regulator. More importantly, however, this product is capable due to its highly sorptive character to be further formulated into a product exceptionally highly loaded with adjuvants and particularly surfactants.Type: GrantFiled: January 3, 1997Date of Patent: February 10, 1998Assignee: Monsanto CompanyInventors: Richard M. Kramer, Thomas M. Day, Ralph E. Lindemann, Jr., Jane L. Gillespie
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Patent number: 5710100Abstract: The disclosure herein relates to the use of certain amides of dichloroacetic acid and other compounds as safener/antidotal compounds to reduce the phytotoxicity to crop plants, especially corn, of imidazolinone-type herbicides alone or in admixture with other co-herbicidal compounds, e.g., .alpha.-haloacetamides.Type: GrantFiled: December 29, 1994Date of Patent: January 20, 1998Assignee: Monsanto CompanyInventors: Brett Hayden Bussler, Ronald Joseph Brinker
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Patent number: 5703273Abstract: A process for preparing N-hydroxyalkylaminomethyl-phosphonic acid or salts thereof which comprises contacting an alkanolamine, formaldehyde and a trialkyl phosphite under suitable reaction conditions to produce a reaction mixture, and hydrolyzing the reaction mixture under neutral, acidic or basic conditions. In one embodiment, the N-hydroxyalkylaminomethylphosphonic acid or salts thereof is catalytically oxidized to produce an N-phosphonomethylaminocarboxylic acid or salts thereof.Type: GrantFiled: July 1, 1996Date of Patent: December 30, 1997Assignee: Monsanto CompanyInventors: Michael K. Stern, Brian K. Cheng, Jerry R. Ebner, Dennis P. Riley
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Patent number: 5703015Abstract: There are provided compositions of certain polyoxyalkylene alkylamine surfactants having eye irritation reduced by the addition of an effective amount of a sulfated polyoxyalkylene alkylphenol, alcohol sulfate, polyoxyalkylene alcohol sulfate, mono- or dialcohol phosphate mono- or di- (polyoxyalkylene alcohol) phosphate, mono-or di- (polyoxyalkylene alkylphenol) phosphate, polyoxyalkylene alkylphenol carboxylate or polyoxyalkylene alcohol carboxylate surfactant. Also provided are pesticidal, particularly herbicidal, compositions comprising polyoxyalkylene alkylamine surfactants having eye irritation reduced by addition of these eye irritation reducing compounds.Type: GrantFiled: December 19, 1994Date of Patent: December 30, 1997Assignee: Monsanto CompanyInventors: Paul D. Berger, Antonio M. Jimenez
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Patent number: 5688994Abstract: A process for the preparation of N-phosphonomethyliminodiacetic acid is disclosed. The process comprises simultaneously infusing into a reaction mixture water, a source of iminodiacetic acid, a source of formaldehyde, and a source of phosphorous acid and strong acid.Type: GrantFiled: December 17, 1996Date of Patent: November 18, 1997Assignee: Monsanto CompanyInventors: Sherrol Lee Baysdon, David Lee Taxter
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Patent number: 5672357Abstract: A method and device for implanting large diameter objects subcutaneously or into the peritoneal cavity of bovines employs a beveled, puncturing, but substantially non-incising trocar.Type: GrantFiled: July 1, 1994Date of Patent: September 30, 1997Assignee: Monsanto CompanyInventors: Clifton Augustus Baile, Jeffrey Wilson Day, Thomas Riley Hampton, II, Thomas Richard Kasser, James Brian Pike, Jonathan Paul Smith, Lyle Elmore Ziemann
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Patent number: 5670162Abstract: A method and device for implanting large diameter objects subcutaneously or into the peritoneal cavity of bovines employs a beveled, puncturing, but substantially non-incising trocar.Type: GrantFiled: June 2, 1995Date of Patent: September 23, 1997Assignee: Monsanto CompanyInventors: Clifton Augustus Baile, Jeffrey Wilson Day, Thomas Riley Hampton, II, Thomas Richard Kasser, James Brian Pike, Jonathan Paul Smith, Lyle Elmore Ziemann
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Patent number: 5665694Abstract: A solid, block detergent containing an alkali metal salt of nitrilotriacetic acid, an acid, alkali metal containing hydroxides and silicates, and alkali metal containing carbonates and sulfates is taught. A process for producing the block detergent is also taught.Type: GrantFiled: March 7, 1995Date of Patent: September 9, 1997Assignee: Monsanto CompanyInventors: Thomas Whitner Backes, Sean Douglas Dingman, Sheldon Philip Verrett
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Patent number: 5656572Abstract: This invention relates to dry, water soluble, agriculturally acceptable herbicidal compositions, to a herbicidal method of use thereof and and to a process for preparing such compositions. This invention also relates to dry, water soluble and/or water dispersible, agriculturally acceptable herbicidal compositions containing two or more herbicides, a herbicidal method of use thereof and to a process for preparing such compositions.Type: GrantFiled: June 5, 1995Date of Patent: August 12, 1997Assignee: Monsanto CompanyInventors: Masuo Kuchikata, Erhard J. Prill, Ronald O. Richardson, Tatsuo Sato, John M. Surgant, Daniel R. Wright
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Patent number: 5612285Abstract: This invention relates to a herbicidal novel dry free-flowing, non-dusty, non-sticky water-soluble granular composition most preferably prepared by extrusion which comprises (a) solid N-phosphonomethylglycine and/or one or more liquid salts thereof or mixtures thereof, (b) one or more liquid surfactants and (c) an extrusion aid which is solid at ambient temperature, the extrusion aid which further comprises a polyalkylene glycol in which the alkylene oxide units are ethylene oxide, propylene oxide, butylene oxide or a mixture of such oxides.Type: GrantFiled: June 5, 1995Date of Patent: March 18, 1997Assignee: Monsanto CompanyInventor: Kristin A. Arnold
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Patent number: 5602276Abstract: A process for preparing N-hydroxyalkylaminomethylphosphonic acid or salts thereof which comprises contacting an alkanolamine, formaldehyde and a dialkyl phosphite in the presence of an alcohol under suitable reaction conditions to produce a reaction mixture, and hydrolyzing the reaction mixture under acidic or basic conditions. In one embodiment, the N-hydroxyalkylaminomethylphosphonic acid or salts thereof is catalytically oxidized to produce an N-phosphonomethylaminocarboxylic acid or salts thereof.Type: GrantFiled: July 1, 1996Date of Patent: February 11, 1997Assignee: Monsanto CompanyInventors: Michael K. Stern, Brian K. Cheng, Jerry R. Ebner, Dennis P. Riley