Patents Represented by Law Firm Morrison & Forerster
  • Patent number: 5378473
    Abstract: Method and laminated composite for administering short or intermediate half-life benzodiazepines such as alprazolam or triazolam transdermally to treat conditions such as anxiety in the case of alprazolam and insomnia in the case of triazolam. The composite comprises an impermeable backing layer and a reservoir layer containing the benzodiazepine and a permeation enhancer combined with a solvent-based acrylic polymer adhesive with the amounts of benzodiazepine and enhancer being sufficient to cause the benzodiazepine to pass through the skin at a rate in excess of about one .mu.g/cm.sup.2 /hr.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: January 3, 1995
    Assignee: Cygnus Therapeutic Systems
    Inventors: Kuldeepak Sharma, Darth M. Dunbar