Abstract: The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.
Type:
Grant
Filed:
July 29, 2008
Date of Patent:
May 4, 2010
Assignee:
Genzyme Corporation
Inventors:
Gary J. Bridger, Eva Maria Boehringer, Zhongren Wang, Dominique Schols, Renato Tony Skerlj, David Earl Bogucki
Abstract: Sputter-deposited amorphous metal oxide films on substrates comprising an aluminum-containing support and a Ni-containing pre-coat reduce Ni ion migration significantly from the substrate onto the top surface of the magnetic recording media. Longitudinal magnetic recording media deposited on metal oxide sealing layers have very good magnetic recording performances and are suitable for high density recording application.
Type:
Grant
Filed:
May 15, 2000
Date of Patent:
July 9, 2002
Assignee:
Seagate Technology LLC
Inventors:
Lin Huang, Liji Huang, Qixu David Chen, Charles Leu, Rajiv Yadav Ranjan