Abstract: Disclosed are methods and systems that include a method for controlling movement of a first unmanned vehicle (UV) to search an area, where the method includes generating a first trace associated with prior positions in which the first UV has been located, determining a direction in which the first UV is to move using the first generated trace, and causing the first UV to move in the determined direction. The trace may be a numerical value that decreases as a function of the time that has elapsed since the first trace was generated. The methods and systems may also include receiving data relating to a second trace, and using that second trace to determine the direction. The second trace may be generated by a second UV. The second trace may be associated with a position within a predetermined radius from a position associated with the first UV.

Abstract: The present invention is related to a compound, preferably a C5a receptor antagonist, having the following structure, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21 and R22 are individually and independently selected from the group comprising H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, arylalkyl, substituted arylalkyl, heteroarylalkyl, substituted heteroarylalkyl, alkoxyl, substituted alkoxyl, aryloxy, substituted aryloxy, arylalkyloxy, substituted arylalkyloxy, acyloxy, substituted acyloxy, halogen, hydroxyl, nitro, cyano, acyl, substituted acyl, mercapto, alkylthio, substituted alkylthio, amino, substituted amino, alkylamino, substituted alkylamino, bisalkyl amino, substituted bisalkyl amino, cyclic amino, substituted cyclic amino, carbamoyl (—CONH2), substituted carbamoyl, carboxyl

Abstract: A liquid culture medium containing photosynthetic organisms dispenses from a droplet generator combined with a screen in the presence of light, and in the presence of a gaseous medium to form a liquid culture medium gas-enriched with the gaseous medium. Specifically, the droplets exiting the droplet generator entrain the gaseous medium. The droplets and entrained gaseous medium then impinge upon a screen. As the droplets and entrained gaseous medium impinge upon the screen, the droplets splatter and change direction and velocity, thereby generating areas of high turbulence around the screen. This high turbulence results in additional and increased mixing of the gaseous medium to create a highly gas-enriched liquid culture medium which promotes improved growth rates and production of the photosynthetic organisms contained therein.

Abstract: A raking attachment for a riding mower supports raking elements in a forward path of a cutting deck. The raking attachment includes a forward extending frame formed by longitudinal frame members positioned with first ends rigidly attached to a riding mower frame and with a second end forming attaching points at a fixed height off the ground. A transverse frame is pivotally attached to the forward extending frame by pivot posts. A rake assembly with at least one row of flexible rake tines disposed across the entire transverse width of the cutting deck is attached to the transverse frame and pivots therewith to contact the ground surface for raking. The rake tines can be raised to a non-raking position or the downward force of the rake tines against the ground surface can be varied by varying the pivot angle of the transverse frame over a range of pivot angles.

Abstract: Devices for the provision of a coating on an implantable medical device are provided. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating.

Abstract: A non-polymeric or biological coating applied to radially expandable medical delivery device provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The delivery device is expanded using the pressure of an inflation fluid. After expanding the delivery device to a pre-determined size and shape, the inflation fluid weeps through the porous surface of the delivery device. The coating releases the delivery device and floats on the inflation fluid until bonding to the tissue due to its affinity for the tissue. Once the coating bonds or affixes to the tissue, through an absorption mechanism by the tissue cells of the coating material, the coating and any therapeutics contained therein are delivered to the tissue. The fluid can contain a therapeutic agent, or can be otherwise biocompatible and/or inert.

Abstract: A composition having at least one modified or derivative of 1,4,6-androstatriene-3,17-dione (“ATD”) will improve the health of mammalian subjects. The improvement of health is achieved with the administration of an effective amount of at least one modified or derivative of 1,4,6-androstatriene-3,17-dione. Particularly, health is improved for a subject suffering with a gynecomastia and/or estrogen-dependent cancer. Also, subjects recovering from steroid misuse/abuse will benefit from treatment in accordance with the present invention.

Abstract: A system and method for the treatment of body tissue is provided that includes a radiation-emitting device and a massaging mechanism. In accordance with one embodiment, the radiation-emitting device is a laser and the massaging mechanism is an automated mechanical massaging mechanism. The radiation-emitting device can emit radiation in one or both of the visible and infrared wavelengths. The radiation-emitting device can emit radiation in a concentric combination of infrared and visible laser light. The method of using the tissue treatment system includes exposing a skin surface of a patient to radiation emitted from the radiation-emitting device at predetermined wavelengths for predetermined periods of time. The method further provides for massaging the exposed skin surface of the patient with the massaging mechanism. The tissue treatment system can be utilized to effect the reduction of excess cellulite.

Abstract: A novel system, method and computer program product for storing and enabling access to certain digital media files of pre-determined formats stored in a centralized media storage device. The system stores digital audio and video media files in a centralized fashion and enables access to one or more independent users via individual workstations.

Abstract: An Ethernet PHY hardware device supports Ethernet MAC SDH/SONET Automatic Protection Switching (APS) functionality for managing protection from failures and recovery from failures on an Ethernet network. An Ethernet PHY sublayer stored on the Ethernet PHY hardware device is configured to monitor working and protect channels and generate an interrupt upon detection of a hard failure or a soft failure. Upon detection of port failures or link failures, the Ethernet PHY sublayer generates the interrupt to invoke an Ethernet MAC Client APS Controller configured to generate and terminate APS requests on working and protect channels to manage protection of working and protect channels from failures and recovery from failures on the Ethernet network. The Ethernet PHY hardware device is configurable for use with a plurality of different network topologies to manage protection from hard or soft failures and recovery from hard or soft failures on the Ethernet network using the Ethernet PHY sublayer.

Abstract: An Ethernet MAC sublayer is provided for supporting Ethernet MAC circuits in an Ethernet Network. In accordance with one embodiment, an Ethernet MAC sublayer is provided for processing and setting up circuits. The MAC sublayer provides support for higher level signaling and routing applications to implement Ethernet MAC circuit functionality. The MAC sublayer provides interrupts for WAN learning and circuit setup. The MAC sublayer also provides address table entry extension to allow for usage of multiple links between nodes. The routing application is used to manage routing information, maintain a MAC to port mapping database, and manage port resources. The signaling application is used to set up and manage circuits. In accordance to various embodiments, circuits of various types and properties can be managed in the Ethernet Network.

Abstract: The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified.

Abstract: A method makes use of a minimally-shearing feeder mechanism supplying a desired flow of particulate solids mixture, with minimal to no sifting segregation to a desired location. The feeder methodology maintains a uniform concentration of each size of particle within the mixture.

Abstract: Presently disclosed is a hydraulic pump device and use thereof, especially in a fluid delivery system. In one embodiment, the fluid delivery system is an inexpensive, single-use device for slow dosing medicament applications. The fluid delivery system may employ a spring-compressed bellows crank or other combination of simple mechanisms operating according to the well-known peristaltic principle to force a volume of ultrapure bio-inert hydraulic fluid through an aperture, thereby expanding one chamber of a two chamber hydraulic cylinder. The second, fluid storage chamber, containing the medicament, is emptied through a conventional orifice in response to the expansion of the pump chamber. The medicament may thence flow through any suitable infusion set into a patient removeably attached thereto.

Abstract: Methods identifying prostate cancer, methods for prognosing and diagnosing prostate cancer, methods for identifying a compound that modulates prostate cancer development, methods for determining the efficacy of a prostate cancer therapy, and oligonucleotide microarrays containing probes for genes involved in prostate cancer development are described.

Abstract: Fluid delivery and measurement systems and methods are disclosed.

Abstract: Disclosed is a transgenic knockout mouse whose genome comprises a homozygous disruption in its endogenous FcRn gene. The homozygous RcRn disruption prevents the expression of a functional FcRn protein, resulting in a transgenic knockout mouse in which exogenously administered IgG1 exhibits a substantially shorter half-life, as compared to the half-life of exogenously administered IgG1 in a wild-type mouse. The transgenic knockout mouse with a homozygous RcRn disruption is also unable to absorb maternal IgG in the prenatal or neonatal stage of development. Also disclosed is a transgenic knockout mouse comprising a homozygous FcRn disruption and a human FcRn transgene. The transgenic addition of human FcRn results in a substantial increase in the half-life of exogenously administered human IgG1. Methods of using the transgenic knockout mouse, and cells derived from them, are also disclosed.