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Patents
Patents Represented by Law Firm Mueting, Baasch, Gebhardt & Schwappach, P.A.
Patents Represented by Law Firm Mueting, Baasch, Gebhardt & Schwappach, P.A.
Positively charged oligonucleotides as regulators of gene expression
Patent number:
5734040
Abstract:
This invention relates to oligonucleotides with ethylenediamine phosphoramidate internucleoside linkages useful for binding to eukaryotic duplex DNA to inhibit or alter gene expression.
Type:
Grant
Filed:
March 21, 1996
Date of Patent:
March 31, 1998
Assignee:
University of Iowa Research Foundation
Inventors:
Daniel L. Weeks, John Dagle