Abstract: The invention concerns a control device for adjusting the relative angular position of a driven shaft, particularly a camshaft of an internal combustion engine, said device comprising a drive pinion that is rotatably connected to the shaft, an adjusting element (1) for the angular adjustment of the drive pinion relative to the shaft, two chambers (2, 3) that are alternately supplied with hydraulic fluid and a control valve (6) for actuating the adjusting element (1), said control valve being connected to the chambers (2, 3) of the adjusting element (1) through pressure medium channels (4, 5). The control valve (6) comprises a valve body (7) that has two working connections A and B for the pressure medium channels (4, 5), a delivery connection P for the supply of hydraulic fluid and a discharge connection T for the discharge of hydraulic fluid, and the control valve (6) further comprises a sliding valve control piston (8) for setting different hydraulic resistances W between the individual connections.

Abstract: The invention concerns novel mikanolide derivatives, their preparation method and their therapeutic uses, in particular as anti-cancer and anti-viral agents.

Abstract: The image forming method carries out reverse development with a developer that has a toner prepared by agglomerating resin particles in a water based medium.

Abstract: Compounds of formula wherein the substituents are as defined in the specification which compounds are useful for inhibiting the activity of NO-synthase enzymes.

Abstract: A concentrated color developer composition packed in a container which is comprised of material exhibiting an oxygen permeability of not more than 50 ml/(m2·day·atm), and the concentrated color developer composition comprising a hydroxyalkyl-substituted p-phenediamine type color developing agent of not less than 0.05 mol/l, a sulfite and a hydroxylamine salt. The processing method by use of the concentrated composition is also disclosed.

Abstract: The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the amount of guest complexed, and decrease the particle size of the complex.

Abstract: The present invention relates to new chiral salen catalysts and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst. More particularly, the present invention is to provide novel chiral salen catalysts and their uses for producing chiral compounds having high optical purity to be used as raw materials for preparing chiral medicines or food additives in a large scale economically, wherein the chirl salen catalyst having a particular molecules structure can be reused continuously without any activating process of used catalysts and cause no or little racemization after the reaction is completed because it maintains its catalytic activity after the reaction process.

Abstract: A shaped part made from a strip, peripherally contiguous ends of the strip being firmly connected to each other is characterized in that a recess (6) is arranged on one end of the strip (1) and an over-dimensioned projection (7) is arranged on the other end of the strip (1), and after bending round of the strip (1), said ends are fit into each other in axial or radial direction so that through a plastic deformation, an undetachable interference fit results between said ends.

Abstract: An optical compensation film comprising a cellulose ester film is disclosed. In the film, (a) each of photoelastic coefficient C(md) in a mechanical direction and photoelastic coefficient C(td) in the transverse direction of the cellulose ester film is 1×10?9 to 1×10?13 Pa?1 and C(md)<C(td), (b) retardation R0 within the plane of the cellulose film defined by Formula (I) is 20 to 70 nm, (c) retardation Rt of the cellulose ester film in a thickness direction, defined by Formula (II) is 70 to 400 nm, and (d) both of a dimensional variation ratio S(md) in the mechanical direction and a dimensional variation ratio S(td) in the transverse direction of the cellulose ester film prior to and after being allowed to stand at ambient conditions of 80° C. and 90 percent relative humidity for 50 hours are ?1 to 1 percent, and |S(md)|>|S(td)|.

Abstract: The invention relates to a device for maintaining grass fields, provided with a frame (1) movable along a ground surface, supporting on one or more support wheels (2), a gearbox with power take-offs (5), a steering handle (11), a drive motor (10), and with exchangeable working attachments which can be fixedly connected to the device and another support wheel (7) on one side adjacently of this working attachment which can be connected fixedly, pivotally or for active steering to the frame with a supporting arm (8) which is adjustable in position and lockable.

Abstract: All possible isomeric forms of a compound of the formula where the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts useful as antibiotics.

Abstract: The invention concerns a product comprising at least a NO synthase inhibiting substance associated with at least a phospholipase A2 inhibiting substance, separately or combined, for simultaneous therapeutic use, separately or spread over time for treating pathologies in which nitrogen monoxide and/or phospholipases A2 are involved. The invention also concerns a pharmaceutical composition comprising, an active principle, at least a NO synthase inhibiting substance and at least a phospholipase A2 inhibiting substance, and optionally a pharmaceutically acceptable.

Abstract: The present invention relates to the chemical modification of single chain polypeptides by means of covalent attachment of strands of poly(ethylene glycol) PEG and similar poly(alkylene oxides) to single chain polypeptide binding molecules that have the three dimensional folding and, thus, the binding ability and specificity, of the variable region of an antibody. Such preparations of modified single chain polypeptide binding molecules have reduced immugenicity and antigenicity as well as having a longer halflife in the bloodstream as compared to the parent polypeptide. These beneficial properties of the modified single chain polypeptide binding molecules make them very useful in a variety of therapeutic applications. The invention also relates to multivalent antigen-binding molecules capable of PEGylation. Compositions of, genetic constructions for, methods of use, and methods for producing PEGylated antigen-binding proteins are disclosed.

Abstract: Disclosed is a printing plate precursor composed of a substrate and provided thereon, a hydrophilic layer having a center line average roughness Ra of from 150 nm to less than 1000 nm and having effective protrusions of from 500 to less than 3000 per mm2, the effective protrusions protruding from an upper plane 1.0 ?m farther from the substrate than a center roughness plane in the three dimensional roughness plane of the hydrophilic layer, and having a ratio H/D of not less than 0.15, wherein H represents a height (?m) from the upper plane of the effective protrusions, and D represents a size (?m) of solids formed by the upper plane and the curved surface protruding from the upper plane of the effective protrusions.

Abstract: The present invention relates to a microbioligcal test method for detecting antibacterial compounds in liquid samples such as milk, meat juice, serum and urine. The method employs an acid-base or redox indicator to detect growth of a test organism and is characterised in that a thermophilic strain of Bacillus or Streptococcus, e.g. Bacillus stearothermophilus var. calidolactis C953, is employed at a concentration of above 107 CFU/ml, preferably between 2×107 and 3×108 CFU/ml.

Abstract: (2S)-2-(Adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester, its preparation and its use The present invention relates to (2S)-2-(adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester of the formula I and its physiologically tolerable salts, their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them. The compound of the formula I and its physiologically tolerable salts are valuable pharmacologically active compounds which can be used, for example, in the treatment or prophylaxis of diseases which can be influenced by inhibiting the vitronectin receptor, for example of bone diseases such as osteoporosis.

Abstract: A process for preparing solutions of sulfonated arylphosphines comprising reacting arylphosphines with oleum, diluting the sulfonation mixture with water, extracting the diluted sulfonation mixture with a solution of a water-insoluble organic solvent, reacting the organic phase with a solution of an inorganic base in water, adjusting the resulting aqueous solutin of sulfonated arylphosphines to a pH of up to 3 by addition of an acid, and passing an inert gas stream through the aqueous solution comprising sulfonated arylphosphines until sulfur is no longer liberated from the aqueous solution of sulfonated arylphosphines.

Abstract: This invention relates to an image forming apparatus having, on the upper surface of an apparatus main body, an operating section which is divided into an operating surface unit in which the angle of an operating surface with respect to a horizontal plane can be changed, and an operating section external unit formed outside the operating surface unit and including at least an upper-surface corner end of the apparatus main body. The apparatus includes an angle holding member for holding the angle of the operating surface with respect to the horizontal plane, a plurality of locking portions formed on the apparatus main body, and a plurality of locking target portions which are formed on the angle holding member and the operating surface unit and which can respectively be locked by the plurality of locking portions.