Abstract: The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders such as cancer.
Type:
Grant
Filed:
October 9, 2009
Date of Patent:
September 13, 2011
Assignee:
Myrexis, Inc.
Inventors:
Ashok Bajji, Se-Ho Kim, Rajendra Tangallapally
Abstract: Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
Type:
Grant
Filed:
July 3, 2007
Date of Patent:
August 2, 2011
Assignee:
Myrexis, Inc.
Inventors:
Sui Xiong Cai, Mark B. Anderson, Adam Willardsen, Nilantha Sudath Sirisoma, Hong Zhang, Kazuyuki Suzuki
Abstract: The present invention provides methods for preventing and treating HIV infection and AIDS by introducing cells displaying HIV late-domain phenotype into a patient, or by administering to a patient nucleic acids, polypeptides or small organic compounds to cause the formation of cells displaying HIV late-domain phenotype in the body of the patient.
Type:
Grant
Filed:
December 20, 2002
Date of Patent:
May 17, 2011
Assignee:
Myrexis, Inc.
Inventors:
Adrian Hobden, Kenton Zavitz, Scott Morham