Abstract: A method of reducing tissue injury in humans or other animal species using a monoclonal antibody to inhibit specific phagocyte functions. The monoclonal antibody is selected to bind to phagocytic leukocytes for the purpose of inhibiting migration to an inflammatory site in the body and to inhibit the adhesion and spreading of activated leukocytes reaching such an area and then, block release of toxic substances by these cells. The monoclonal antibody is administered in vivo prior or early in the course of an experience leading to an injurious inflammatory response such as can result from restoration of myocardial blood flow interrupted by an acute coronary thrombosis.

Abstract: A hybrid cell line capable of producing monoclonal antibodies uniquely specific to human neutrophils. The monoclonal antibody has no reactivity with other human peripheral blood cells and virtually no reactivity with granulocyte precursors or other cells in bone marrow. Further, there is no reactivity with human acute leukemia cells. One of the partners in the hybridoma fusion of a mouse spleen cell developed from using highly purified human granulocytes as the immunization agent. The monoclonal antibody further is characterized by its capability of being used to enumerate and isolate neutrophils in normal peripheral blood and patients with acute leukemia.

Abstract: A security lock for a double-hung sash window assembly which is to be mounted on a stile of one of the sash frames to limit movement of the second sash frame relative to the one sash. The lock includes a casing adapted to be mounted within a recess formed in one of the sash frames, a faceplate of the casing having an opening therein communicating with an interior casing cavity. A tumbler pivots in the cavity and is spring biased to normally project through the opening to engage the second sash. A leaf spring is mounted completely within the casing cavity normally to bias the tumbler into its locking position, but permitting the tumbler to be retracted into the casing. The lock can be supplied as an assembled unit for installation.

Abstract: An adjustable support structure for an operating equipment that is adjustable in a plurality of directions so as to enable level mounting of the equipment with respect to the horizontal plane on a roof surface, for instance. The adjustable support structure includes a base member, a support member capable of accepting and supporting a desired piece of equipment, and means for adjustably coupling the support member to the base member including adjusting the position of the support member in a plurality of directions and maintaining the support member in a desired position with respect to the base member. The support structure can be used on a plurality of surfaces that are either relatively flat and level with respect to the horizontal plane or are inclined.

Abstract: A pre-assembled latch for mounting externally on the header of a pivotal sash window of a double-hung sash window assembly. The latch includes a housing having a spring-biased latch bolt normally providing a protruding bevelled formation for engaging a guide rail of the window assembly. The housing has depending spring clip means integral therewith for retaining the latch bolt operably assembled in the housing and the latch bolt has means cooperating with the housing for retaining the spring means in biasing association with the latch bolt.

Abstract: A hybrid cell line is provided which is capable of producing monoclonal antibodies which bind to HIV core antigen P55, the precursor protein coded for the gag gene, the core protein P24 and partial breakdown products P39 and P33. The monoclonal antibody embodying the invention does not bind the P18 core protein or any HIV envelope antigens. The cell line of the invention was developed by a unique immunization protocol in which BALB/c mice were immunized over a series of multiple infusions using a select group of immunogens and a conventional myeloma cell line for fusion with the murine splenocytes harvested.The monoclonal antibody is identified as the KC-57 antibody. This monoclonal antibody is especially useful for a solid phase immunoassay in which the monoclonal antibody is detected in its binding to HIV antigens found in a serum or plasma sample from a human patient. The cell line which produces the KC-57 monoclonal antibody has been deposited in the American Type Culture Collection, Rockville, Md.

Abstract: An inflatable plastic structure simulating a beverage can or bottle with a capped end. The upper end of the structure is provided with an annular lip projecting vertically from the peripheral edge thereof. The lip is adapted to be folded down over the end of the structure, and may be provided with a tubular ring inflatable separately from the structure to resemble the rim of a beverage can.

Abstract: A solid-phase immunoassay is provided for determination of HIV antigens in human physiological fluid. The immunoassay is characterized by the coating of a solid substrate with a unique monoclonal antibody which recognizes a common antigenic determinant of a group of HIV core antigens and no HIV envelope antigens of HIV. The test sample preferably also is subjected to a lysing reagent prior to the incubation for uniformly dispersing antigens which may be present in the test sample.

Abstract: A solid-phase immunoassay is provided for determination of members of an immunological pair such as antigen and/or antibody of a single binding pair in human physiological fluid, wherein a single immunoassay enables simultaneous detection of antigen and/or antibody of a single binding pair in a test sample which may have circulating antigen and/or antibody. The immunoassay is characterized by the addition of an amount of antigen or "spike" of the binding pair to the test sample prior to incubation of the test sample in the presence of a solid-phase absorbed antibody of the binding pair. The test sample preferably also is subjected to a lysing reagent prior to the incubation for uniformly dispensing antigens which may be present in the test sample.

Abstract: A chair which includes a seat frame having depending leg members and a pair of upstanding, spaced apart members arranged to provide a lower backrest part for the chair and an upper backrest frame part having a pair of spaced apart depending members in registry with the upstanding members, said members being hollow with open extremities, and flexible spring means secured between each pair of members to provide an articulated, flexible spring backrest for the chair. Each flexible spring means includes an elongated, flat or blade spring member having its opposite ends secured within a holder member which is closed at one end and open at its opposite end for inserting the spring into the holder. The open ends of each holder have stop flange formations protruding outwardly thereon which, when the holders are spaced apart at their open ends with a slight gap therebetween, effect limitation of the angle of flexure of the spring by engagement of the flanges one with the other.

Abstract: A hybrid cell line capable of producing monoclonal antibodies uniquely specific to human neutrophils and eosinophils and exhibiting no specificity for lymphocytes, basophils and monocytes. Further there is noreactivity with acute leukemia cells. One of the partners in the hybridoma fusion of a mouse spleen cell developed from using human granulocytes as the immunization agent. The monoclonal antibody further is capable of being used to enumerate and isolate neutrophils in normal peripheral blood and possibly in blood of patients with acute leukemia.

Abstract: A method of reducing tissue injury in humans or other animal species using a monoclonal antibody to inhibit specific phagocyte functions. The monoclonal antibody is selected to bind to phagocytic leukocytes for the purpose of inhibiting migration to an inflammatory site in the body and to inhibit the adhesion and spreading of activated leukocytes reaching such an area and then, block release of toxic substances by these cells. The monoclonal antibody is administered in vivo prior or early in the course of an experience leading to an injurious inflammatory response such as can result from restoration of myocardial blood flow interrupted by an acute coronary thrombosis.

Abstract: A pre-assembled latch for mounting externally on the header of a pivotal sash window of a double-hung sash window assembly. The latch includes a housing having a spring-biased latch bolt normally providing a protruding bevelled formation for engaging a guide rail of the window assembly. The housing has means integral therewith for retaining the latch bolt operably assembled in the housing and the latch bolt has means cooperating with the housing for retaining the spring means in biasing association with the latch bolt.

Abstract: Murine monoclonal antibodies specific to unique antigenic determinants on mammalian terminal deoxynucleotidyl transferases (TdT). The monoclonal antibodies specifically bind to TdT in a wide variety of mammalian cells including human, mouse, rat, rabbit and bovine origin. The monoclonal antibodies are secreted by hybridoma cells derived from fusion of murine plasmacytoma cells with splenocytes from mice immunized with TdT from bovine thymus cells. The monoclonal antibodies can detect small numbers of TdT-positive cells for monitoring of TdT-positive leukemias and lymphomas in multiple species, including human.

Abstract: An animal food dispensing machine capable of being operated by a domesticated animal or pet includes a housing provided with a discharge chute, a food storage compartment, a free-wheeling external actuator, and a measuring dispenser mechanism complete the device. In one embodiment of the dispenser, a lower plate is rotatable about a boss and aligns an opening with the discharge chute to discharge a quantity of food therethrough to an outlet. An upper plate mounted in a fixed position guides the food to the lower plate. In another embodiment of the dispenser, a metering plate is included to control a measured quantity of the food to be dispensed. The free-wheeling external actuator assembly coupled to the internal dispenser mechanism is activated by the animal to effect discharge of the metered quantity of food through the discharge chute in the housing in relation to the angular distance through which the actuator assembly is moved by the animal.

Abstract: A single or multiple drapery track and mounting bracket therefor. A cooperating locking latch is provided for mounting the track to the bracket quickly and without using tools. The track has a longitudinal bead along one edge and a dependant wall spaced therefrom. The dependant wall has an outer inclined face having at least one longitudinal notch. The mounting bracket is generally L-shaped, the horizontal leg carrying a downwardly opening curl of size and configuration to receive the bead. The other leg has an inwardly canted strut or tongue of limited resilience. The mounting bracket is first installed on a vertical wall and the longitudinal bead of the support engaged within the curl. The track is pivoted toward the horizontal leg of the bracket forcibly flexing the tongue until it is tightly engaged within the notch. To dismount the track, the tongue is manually flexed until free of the notch and then, the track is pivoted in the reverse direction until free of the bracket.

Abstract: A chemical agent is provided for significantly preventing or blocking non-specific staining or binding of an antibody specific for Terminal deoxynucleotidyl Transferase (TdT) during immunofluorescent or immunoperoxidase assay procedures. These procedures include both immunofluorescent and immunohistochemical staining of samples followed by flow cytometric and/or microscopic analysis, respectively. The invention is practiced by selective use of casein introduced into the assay procedures at an appropriate interval prior to analysis using a labelled or tagged monoclonal antibody specific to a TdT epitope. The casein utilized successfully was obtained from a large variety of sources and includes the use of a non-fat milk product.

Abstract: A control slide for use in an immunoassay having a section of a cell pellet retained on the slide in a stable and substantially permanent formation which can be stored at room temperature. Further, the invention includes the method of making the control slide.

Abstract: A window shade for a motor vehicle is made of a generally rectangular sheet of material and provided with substantially straight upper, lower and side edges. The sheet is provided with an axial fold line and a plurality of radial fold lines emanating from the approximate intersection of the axial fold line and the bottom edge and extending between the top and the side edges to form a plurality of triangular panels and to permit the sheet to fold in accordion fashion.