Abstract: There is provided an objective lens driving device, wherein a lens holder for holding an objective lens and a coil unit is connected with and floatingly supported by a base block using a plurality of elongate flexible metal members. The objective lens driving device is formed by positioning a plurality of elongate flexible metal members at the predetermined positions with respect to the lens holder and the base block which are to be formed, forming the lens holder integrally connected with one end of each elongate flexible metal member, forming the base block integrally connected with the other end of each elongate flexible metal member, attaching the objective lens and the coil unit in the lens holder.

Abstract: Heteroaryl-3-oxo-propanenitrile derivatives of formula (I) ##STR1## wherein X represents an oxygen atom or a --CH(R.sub.4)--, --O--CH(R.sub.4)--, --S(O).sub.n --CH(R.sub.4)--, --CH(R.sub.4)--O--, --CH(R.sub.4)--S(O).sub.n -- or --CH(R.sub.4)--CH.sub.2 -- group wherein n is 0, 1 or 2; R.sub.1 represents C.sub.1 -C.sub.6 alkyl, pyridyl or unsubstituted or substituted phenyl; R.sub.2, R.sub.3, and R.sub.4 are as herein defined; and Q is hydrogen, carboxy, C.sub.2 -C.sub.7 -alkoxycarbonyl or a --CON(R.sub.a)R.sub.b group, R.sub.a and R.sub.b being as defined herein; and their pharmaceutically acceptable salts are useful in the preparation of pharmaceutical compositions active in the treatment of autoimmune diseases.