Patents Represented by Attorney Nancy J. DeSantis
  • Patent number: 5744305
    Abstract: A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 28, 1998
    Assignee: Affymetrix, Inc.
    Inventors: Stephen P.A. Fodor, Lubert Stryer, J. Leighton Read, Michael C. Pirrung