Patents Represented by Attorney Nancy J. Gettel

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  • Compounds as cannabinoid receptor ligands
    Patent number: 8338467
    Abstract: Disclosed herein are compounds of formula (I) wherein R1, R2, R3, R25a, R26a, X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: December 25, 2012
    Assignee: AbbVie Inc.
    Inventors: Teodozyj Kolasa, Jennifer M. Frost, Meena V. Patel, Steven P. Latshaw, Arturo Perez-Medrano, Xueqing Wang, Karin Rose Marie Tietje, Sridhar Peddi, William A. Carroll
  • Compounds as cannabinoid receptor ligands
    Patent number: 8338623
    Abstract: The present application relates to cannabinoid receptor ligands containing compounds of formula (I) wherein A, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Grant
    Filed: July 8, 2008
    Date of Patent: December 25, 2012
    Assignee: AbbVie Inc.
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Derek W. Nelson
  • Compounds as cannabinoid receptor ligands
    Patent number: 8288428
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Ring A and R1 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: October 16, 2012
    Assignee: Abbott Laboratories
    Inventors: Xueqing Wang, Jennifer M. Frost, Michael J. Dart, Bo Liu
  • Substituted pyrimidine derivatives
    Patent number: 8278311
    Abstract: The present application describes substituted pyrimidine compounds of formula (I) wherein X, A1, R1, R2, R3, R4, R5, R6, R7, R8, R9, p, q, r, v, and w are defined in the specification, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: October 2, 2012
    Assignee: Abbott Laboratories
    Inventors: Huaqing Liu, Irene Drizin, Marlon D. Cowart, Robert J. Altenbach
  • Macrocyclic spiro pyrimidine derivatives
    Patent number: 8278313
    Abstract: Macrocyclic Spiro pyrimidine compounds of formula (I): compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: October 2, 2012
    Assignee: Abbott Laboratories
    Inventors: Huaqing Liu, John R. Koenig, Marlon D. Cowart, Lawrence A. Black
  • Amino heterocyclic linked pyrimidine derivatives
    Patent number: 8268846
    Abstract: Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: September 18, 2012
    Assignee: Abbott Laboratories
    Inventors: Brian D. Wakefield, Robert J. Altenbach, Lawrence A. Black, Marlon D. Cowart, Irene Drizin, Huaqing Liu
  • 3,9-diazaspiro[5,5]undecane amides and ureas and methods of use thereof
    Patent number: 8268853
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders ameliorated by ?4?2 positive allosteric modulators. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for using such compounds and compositions, and a process for preparing the compounds.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: September 18, 2012
    Assignee: Abbott Laboratories
    Inventors: Michael R. Schrimpf, Diana L. Nersesian, Chih-Hung Lee, Ramin Faghih, Gregory A. Gfesser
  • Compounds as cannabinoid receptor ligands
    Patent number: 8236822
    Abstract: Cannabinoid receptor ligands of formula (I) wherein Ring A and R1 are as defined in the specification. Compositions including such compounds, and methods of treating conditions and disorders using such compounds and compositions are also described.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: August 7, 2012
    Assignee: Abbott Laboratories
    Inventors: Xueqing Wang, Michael J. Dart, Bo Liu
  • Compounds as cannabinoid receptor ligands
    Patent number: 8188135
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein A1, A5, Rx, X4, and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: May 29, 2012
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Steven P. Latshaw, Teodozyj Kolasa, Tongmei Li, Sridhar Peddi, Bo Liu, Arturo Perez-Medrano, Meena Patel, Xueqing Wang, Derek W. Nelson
  • Compounds as cannabinoid receptor ligands
    Patent number: 8173687
    Abstract: Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Y, X1, X2, X3, R1, and R2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: May 8, 2012
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Jennifer M. Frost, Teodozyj Kolasa, Steven P. Latshaw, Bo Liu, Meena V. Patel, Arturo Perez-Medrano, Xueqing Wang
  • Compounds as cannabinoid receptor ligands and uses thereof
    Patent number: 8158663
    Abstract: The present invention relates to thiazolidinylidene containing compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, and X are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: April 17, 2012
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Tongmei Li, Arturo Perez-Medrano, Sridhar Peddi
  • Benzothiazole and benzooxazole derivatives and methods of use
    Patent number: 8153813
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for using such compounds and compositions, and a process for preparing the compounds.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: April 10, 2012
    Assignee: Abbott Laboratories
    Inventors: Lawrence A. Black, Marlon D. Cowart, Gregory A. Gfesser, Brian D. Wakefield, Robert J. Altenbach, Huaqing Liu, Chen Zhao, Gin C. Hsieh
  • Compounds as cannabinoid receptor ligands
    Patent number: 8058293
    Abstract: Disclosed herein are compounds of formula (I) wherein R1, R2, R3, R25a, R26a, X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: November 15, 2011
    Assignee: Abbott Laboratories
    Inventors: Teodozyj Kolasa, Jennifer M. Frost, Meena V. Patel, Steven P. Latshaw, Arturo Perez Medrano, Xueqing Wang, Karin Rose Marie Tietje, Sridhar Peddi, William A. Carroll
  • Method for reducing side effects of CBreceptor agonist therapy using a combination of a selective CBreceptor agonist and a selective CBreceptor antagonist
    Patent number: 8044071
    Abstract: The present application describes a method of treating pain with a combination of a CB2 cannabinoid receptor agonist and rimonabast.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: October 25, 2011
    Assignee: Abbott Laboratories
    Inventor: William A. Carroll
  • Amide derivatives as positive allosteric modulators and methods of use thereof
    Patent number: 7994223
    Abstract: The invention relates to novel amide derivatives that are positive allosteric modulators of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: August 9, 2011
    Assignee: Abbott Laboratories
    Inventors: Michael R. Schrimpf, Kathleen H. Mortell, Diana L. Nersesian, Chih-Hung Lee, Bruce Clapham
  • Compounds as cannabinoid receptor ligands
    Patent number: 7985768
    Abstract: The present invention relates to thiophene containing compounds of formula (I) wherein R1, R2, R3, and n are as defined in the specification, pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: July 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Derek W. Nelson, Steven P. Latshaw
  • Method for pain treatment
    Patent number: 7985745
    Abstract: This invention discloses a method of treating pain by administering histamine H4 receptor ligands and compositions comprising the same.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: July 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Robert J. Altenbach, Huaqing Liu, Irene Drizin, Neil Wishart, David J. Babinski, Robert J. Gregg, Arthur A. Hancock, Kathryn J. Hancock, legal representative, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield