Abstract: An improved cellulose acetate semi-permeable hollow fiber suitable for use in artificial kidneys and a process for making same.

Abstract: A hollow fiber separatory element of the type having a plurality of hollow semipermeable fibers terminating at their end portions in resin tubesheets; each tubesheet has a disc-shaped portion that tapers radially inwardly toward its inner end surface that serves as a pressure-induced sealing surface when forced into contact with a correspondingly tapered surface on the inner wall of a surrounding jacket. Each tubesheet optionally includes a second tapered portion that extends outwardly from the outer end face of the disc portion and its peripheral surface tapers radially inwardly toward the outer end planar surface which exposes the open ends of the fibers therein. The tubesheet disc portion may be circular, lenticular, elliptical or have other selected shape.

Abstract: A stabilizer for a gun comprising a tubular element is adapted to fit on the muzzle end of a gun barrel or flash hider and is releasably secured in position by a stop carried by a lever pivoted on the element. The lever is yieldably urged by resilient means to move the stop through an opening in the element and into a recess in the barrel or flash hider. A plurality of stabilizing vents are provided in the element for discharging combustion gases from the gun and a plurality of exterior gas directing projections on the element are associated with certain of the vents for directing the gases from all of the associated vents essentially in the same direction to one side of the element.

Abstract: An improved one-piece, integral hollow fiber artificial kidney and a semi-continuous method for making such kidneys and other apparatus of the hollow fiber separatory-type.

Abstract: An improved semi-continuous method for making one-piece, integral hollow fiber artificial kidneys and other apparatus of the hollow fiber separatory type.

Abstract: Apparatus for and method of automatically controlling the quantity and rate of liquid removed from blood during hemodialysis. The apparatus supplies dialysate in a single pass system in a closed, controlled volume circuit which includes an above atmospheric pressure portion and a below atmospheric pressure portion. The above atmospheric pressure portion includes a pair of chambers for alternate supply to and removal of the dialysate from the below atmospheric pressure portion which contains an artificial kidney and a third means for removing fresh dialysate from the above atmospheric pressure portion; the below atmospheric pressure portion includes means which isolates the kidney containing portion and restores pressure to spent dialysate to a pressure at least equal to or higher than the pressure of the dialysate fed into said closed circuit; the above atmospheric circuit also includes means for removing gas from the spent dialysate prior to filling the spent dialysate removal chamber before discard.

Abstract: A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically and/or parenterally, and/or systemically a composition comprising a pharmaceutical carrier and at least one diamino compound selected from the diamines of saturated and unsaturated aliphatic hydrocarbons having 3 to 6 carbon atoms and the diamines of saturated monocarboxylic acids having 4 to 6 carbon atoms and the alkyl esters thereof containing from 1 to 4 carbon atoms. These diamino compounds are usable alone or in combination with certain prostaglandin compounds, certain phosphodiesterase inhibitor compounds and certain cyclic adenosine monophosphate compounds.

Abstract: Apparatus and method for make up of a hemodialysis solution and supply of same to an artificial kidney; the solution optionally contains bicarbonate in any desired amount. The apparatus comprises a recirculation loop which mixes a hemodialysis dialysate concentrate with deaerated water and may include another interconnected recirculation loop adopted to form an aqueous bicarbonate solution. Both recirculation loops mix the concentrates in the recirculation fluid in venturi means operated by continuously controlling the velocity of fluid flowing therethrough to create suction to inject the requisite quantity of concentrate to form the final desired composition in the product hemodialysis solution.

Abstract: A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically and/or parenterally, and/or systemically a composition comprising a pharmaceutical carrier and at least one diamino compound selected from the diamines of saturated and unsaturated aliphatic hydrocarbons having 3 to 6 carbon atoms and the diamines of saturated monocarboxylic acids having 4 to 6 carbon atoms and the alkyl esters thereof containing from 1 to 4 carbon atoms. These diamino compounds are usable alone or in combination with certain prostaglandin compounds, certain phosphodiesterase inhibitor compounds and certain cyclic adenosine monophosphate compounds.

Abstract: The invention comprises an assembled electrical lamp socket construction having novel integral sealing means for the tower end derived from axial installation of a split plug wedging compressively within an outer socket shell and against insulation of wiring passing therethrough to retain electrical circuit contact assemblies in the tower. The plug is inserted with interengaging tapered surfaces in the tower end of the socket shell producing snap-in fit for the circumferential compressive engagement of the plug with the shell and a second interference compressive fit for the mating surfaces of the split plug halves. Apertures for insulated electric wires are formed in the mating surfaces with circumferential protrusions that encapsulate and compressively penetrate the wire insulation to form a seal thereabout.

Abstract: A process for the treatment of psoriasis comprising administering to humans or domesticated animals topically and/or systemically a composition comprising a pharmaceutical carrier and eicosa-5,8,11,14-tetraynoic acid, its congeners, and the lower alkyl esters thereof; in one preferred form of the invention the composition comprises a pharmaceutical carrier and 5,8,11 eicosatriynoic acid; in another preferred form of the invention the composition comprises a pharmaceutical carrier and at least one active compound selected from the groups eicosa-5,8,11,14-tetraynoic acid, its congeners and the lower alkyl esters thereof and at least one compound selected from the group consisting of PGE.sub.1, PGE.sub.2, PGE.sub.3 and the alkyl esters thereof containing from 1 to 8 carbon atoms inclusive, and 13,14-dihydro PGE.sub.1 and the alkyl esters thereof containing from 1 to 8 carbon atoms inclusive.

Abstract: An extra corporeal blood tube injection site comprising a smooth blood conduit or tube, an elongated elastomeric sleeve surrounding a section of the tube, and a C-shaped needle-impenetrable member extending along and partially surrounding the sleeve which generates forces within the portion of the sleeve that is not covered by the C-shaped member sufficient to prevent air leakage into, or blood leakage from, the tube during needle penetration or after withdrawal of a needle.

Abstract: Pharmaceutical compositions administered to humans and animals topically for treatment of proliferative skin diseases, primarily psoriasis. The composition comprises a pharmaceutical carrier with at least one active ingredient selected from the group consisting of para bromophenacyl bromide, alpha tocopherol, mepacrine, chloroquine, hydroxychloroquine, dibucaine, tetracaine, lidocaine, butacaine, procaine, ethylene diamine tetra acetic acid and ethylene glycol bis(.beta.-amino ethyl ether)-N-N' tetra acetic acid; the compositions may also include one or more unsaturated aliphatic compounds, a glucocorticoid and a prostaglandin.

Abstract: A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically or systemically, a composition comprising a pharmaceutical carrier and an indole derivative and combinations thereof with permissive dosages of glucocorticoids.

Abstract: A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one active compound selected from Groups 3, 4, 5, 6, 7 and 8 set forth in the specification, and combinations thereof with a glucocorticoid.

Abstract: A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one active compound selected from certain anilino nicotinic acids used alone, or in mixtures, or in combination with a glucocorticoid.

Abstract: A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one active compound selected from the groups, substituted alkyl zanthines, substituted thioxanthines, alone or in combination with a glucocorticoid.

Abstract: A method of potting in a single or multi-cavity mold a plurality of fibers in continuous tow form to encapsulate the fibers, fill the interstices and form a solid tubesheet of selected shape and length. After transversely cutting through the thus formed tubesheet and the fibers therein a pair of tubesheets are formed each attached to and forming the end portion of a length of fibers. Potting at spaced longitudinal locations on the continuous tow, and transverse cutting, produces fiber bundle assemblies having a length of the tow of hollow fibers between a pair of axially spaced tubesheets. The process is semi-continuous or continuous, as desired.