Abstract: Genes isolated from Neisseria memingitidis, as well as isolated nucleic acids, probes, expression cassettes, polypeptides, antibodies, immunogenic compositions, antisense nucleic acids, amplification mixtures, and new invasion deficient swains of Neisseria meningitidis are provided Methods of detecting Neisseria meningitidis and Neisseria meningitidis nucleic acids, and methods of inhibiting the invasion of mammalian cells by Neisseria meningitidis are also provided.
Type:
Grant
Filed:
August 17, 1999
Date of Patent:
October 29, 2002
Assignee:
Centers for Disease Control and Prevention, as represented by
the Secretary, Department of Health and Human Services
Inventors:
Efrain M. Ribot, David S. Stephens, Nigel Raymond, Frederick D. Quinn