Abstract: The invention relates to transgenic non-human animals capable of producing high affinity human sequence antibodies. The invention is also directed to human sequence antibodies specific for human antigens , such as, human CD4. The invention also is directed to methods for producing human sequence antibodies.

Abstract: A mechanism for using stream objects in stream processing operations is provided. A definition of a class of stream objects used in stream processing algorithms can define output and update operations included in instances of the stream objects and the API (application programming interface) through which they may be called. The class definition may further include the type of state information to be held by the instantiated stream objects. An instance of the stream object may be instantiated in a text-based computing environment and the operations may be used to process streams of data.

Abstract: The present invention provides a graphical model in a computing environment that enables a non-graphical entity to be a caller entity that executes a sequence of commands to call to a graphical or non-graphical entity that is a callee. The present invention also enables a graphical entity to be a caller to call a non-graphical entity as a callee. The present invention further allows graphical entities to have a variable number of input ports and output ports and provides the ability to use function overloading that is similar to function overloading provided in textual programming languages, such as C and C++. Further, the present invention allows the use of hyperlink between navigate between the caller and callee entities.

Abstract: The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vitro with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells.

Abstract: An anonymous authentication-based private information management (PIM) system and method are provided. The PIM method includes receiving an anonymous certificate not including user information from an anonymous certification authority; generating an anonymous document including the anonymous certificate and some of the user information; and providing the anonymous document to a web service provider so as to be authenticated and thus provided with a web service by the web service provider. Thus, only a minimum of user information may be provided to the web service provider. In addition, it is possible to strengthen a user's right to self-determination and control over the exposure and use of his or her personal information by allowing a user to manage his or her own personal information or entrusting the PIM server to manage user information. Moreover, it is possible to protect the privacy of a user by preventing the exposure of user information.

Abstract: A modular camera having a chassis module, a camera module, an illumination module and a communications module that together form a cooling passageway. The chassis module has a back wall having a first end and an opposite second end, a bottom wall having at least one opening formed therein, a first fan mounted at the chassis back wall first end, and a second fan mounted at the chassis back wall second end. The camera module has a body, wherein the camera body is removably received through a hole formed through the chassis module back wall. The illumination module has a back wall, wherein the illumination module is removably coupled to the chassis module so that the illumination module back wall is spaced apart from the chassis module back wall. The communication module is removably coupled to the chassis module. The chassis module back wall, the camera module body, the illumination module back wall and the communications module together form a cooling channel.

Abstract: Pre-lookup index search blocks and multidimensional interpolation blocks that use the results of the pre-lookup index search blocks in a block diagram to graphically specify (and perform) multidimensional interpolation calculations. The pre-lookup index search and interpolation blocks are defined so as to provide for a separation of breakpoint set data and table data, thus enabling a user to explicitly manage the use of common breakpoint set data. A block diagram created using pre-lookup index search blocks and interpolation using pre-lookup index search blocks shows all tables that use a particular breakpoint set via graphical connections on the block diagram between the pre-lookup index search blocks and the interpolation using pre-lookup index search blocks.

Abstract: An integrated system for modeling, simulating and analyzing chemical and biochemical reactions includes a modeling environment for constructing a model of a chemical or biochemical reaction. The system also includes a simulation engine accepting as input the constructed model of the chemical or biochemical reaction and generating as output an expected result. An analysis environment communicates with the simulation engine and displays the expected result.

Abstract: Provided are an apparatus and method for checking Personal Computer (PC) security. The apparatus includes a check module for checking a security configuration of a PC on the basis of a check policy received from a security check server and outputting check results, and a control module for changing the security configuration of the PC on the basis of a control policy received from the security check server and the check results received from the check module. According to the apparatus, a security check agent installed in each PC performs security check and changes a security configuration according to a control policy, such that the security configurations of PCs in a network can be managed collectively.

Abstract: A method for controlling quality of service (QoS) in a mobile communication system includes configuring a service model to operate radio resources, based on an application to provide a requested service from a subscriber terminal; forming a QoS profile using the service model; allocating the radio resources for each requested services in accordance with the QoS; providing information on the allocated radio resources to the application; monitoring a condition of the allocated radio resource; and controlling the QoS by reflecting information obtained from the monitored condition.

Abstract: A method and apparatus for extracting a windows executable file that can search for a pattern related to windows executable files among a large quantity of network packets using a hardware-based session tracking and pattern matching technology and that can extract all packets included in the corresponding session are provided. The method of extracting a windows executable file includes: collecting incoming packets having a payload according to a session of a reference packet having an MZ pattern; performing a portable executable (PE) pattern matching for the collected incoming packets; and forming a PE file based on at least one incoming packet satisfying the PE pattern matching.

Abstract: A method, system and computer program product is disclosed for providing a distributed computing environment in which an arbitrary job manager or scheduler is able to be plugged. In the distributed computing environment, a job is created in a storage location to include one or more technical computing tasks and submitted to the arbitrary scheduler by transferring a reference to the storage location of the job. Since a reference to the storage location of the job is transferred to the scheduler, the interface with the scheduler can be implemented regardless of the scheduler. The scheduler then transfers the reference to the storage location of the job to one or more remote workers.

Abstract: Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells TH cells or TH17 cells.

Abstract: Methods and systems are provided for a systematic approach to computer aided inventing. In a modeling environment, a model representing any item, composition or process can be defined and configured using the lexicon and specification of an innovation database. In the model, objects can be identified, defined, and configured to provide the model with constituent products, components, features and materials. An innovation engine automatically applies one or more morphs from the innovation database to the objects of the model to generate morphed versions of the model that may provide innovations of or invention to the item, composition or process represented by the model.

Abstract: Methods and systems are provided for automatically generating code from a graphical model representing a design to be implemented on components of a target computational hardware device. During the automatic code generating process, a memory mapping is automatically determined and generated to provide an optimization of execution of the program on the target device. The optimized memory mapping is incorporated into building the program executable from the automatically generated code of the graphical model.

Abstract: A fuel cell system provided with a fuel cell module, a water supply device for supplying water to the fuel cell module, a water container for supplying water to the water supply device, and a condenser for condensing water vapor in the exhaust gas which is discharged from the fuel cell module and supplying the condensed water to the water container. The water container contains therein an ion exchange device for removing impurities which are contained in the water supplied from the condenser. The water supply device is provided below and downstream of the water container. A pressure regulating device for absorbing a pulsation of the water supply device and absorbing the variation in the pressure in the fuel cell module is provided between the water supply device and the fuel cell module.

Abstract: The invention provides methods and compositions for modulating the expression, processing, post-translational modification, stability and/or activity of XBP-1 protein, or a protein in a signal transduction pathway involving XBP-1 to treat dyslipidemias and steatosis disorders. The present invention also pertains to methods for identifying compounds that modulate the expression, processing, post-translational modification, and/or activity of XBP-1 protein or a molecule in a signal transduction pathway involving XBP-1.

Abstract: Provided is a measurement device. The measurement device includes a sensor, a wavelength-tunable light source, an additional light source, a coupler, and an optical power measurer. The sensor accepts a sample. The wavelength-tunable light source irradiates wavelength-tunable light to detect a reaction of the sensor. The additional light source irradiates wavelength-fixed light to detect an initial time of the reaction. The coupler combines the wavelength-tunable light source and the additional light source and irradiates the combined input light on the sensor. The optical power measurer detects the reaction of the sensor from an output light transmitted through or reflected by the sensor.

Abstract: A fuel cell system includes a fuel cell stack, a heat exchanger for heating an oxygen-containing gas using a heat medium before the oxygen-containing gas is supplied to the fuel cell stack, a reformer for reforming a raw fuel chiefly containing hydrocarbon to produce a fuel gas to be supplied to the fuel cell stack, a combustor for burning a raw fuel and an exhaust gas discharged from the fuel cell stack after consumption in power generation reaction to produce a combustion gas as the heat medium, a casing containing the fuel cell stack, the heat exchanger, the reformer, and the combustor. A combustion gas outlet of the combustor is directly opened to a combustion gas inlet of the fluid unit.

Abstract: This invention relates to a flexible intake system for a crankcase scavenged two-stroke internal combustion engine (10) having an additional air supply to its transfer ducts. The intake system comprises a flexible intake duct (22) connecting a fuel supply unit (21) e.g. a carburetor with an engine cylinder (11) and at least one flexible air duct (40) connecting a valve housing (42) for additional air with the engine cylinder. The end portion of the flexible intake duct (22) and at least one air duct (40) is secured to the cylinder by means of a baffle (23) made of a stiffer material than the ducts (22, 40) themselves.