Patents Represented by Attorney Nora Stein-Fernandez
  • Patent number: 7943651
    Abstract: The present invention provides compounds of formula (I): pharmaceutical compositions comprising the compounds and the use of the compounds for the manufacture of a medicament, particularly for the treatment of inflammation and/or allergic conditions.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: May 17, 2011
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Anthony William James Cooper, David House, Iain McFarlane McLay
  • Patent number: 7909527
    Abstract: A dispensing container for application of a fluid film forming substance to a surface, particularly a therapeutic film to a user's skin comprising a reservoir of a fluid film forming substance, a dispensing nozzle for the film forming substance, and a pump to send the substance from the reservoir through the dispensing nozzle. The dispensing nozzle comprises an elongate slot shaped aperture, and the dispensing container is adapted, particularly by a support extending from the side of the dispenser, so the nozzle can move adjacent to the surface in a direction transverse to the length direction of the slot whilst the substance is flowing through the aperture.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: March 22, 2011
    Assignee: Glaxo Group Limited
    Inventor: Timothy Paul King
  • Patent number: 7858796
    Abstract: The invention is directed to novel indole carboxamide derivatives. Specifically, the invention is directed to compounds according to formula I: where R1, R2, R3, U and V are defined below and to pharmaceutically acceptable salts thereof. The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKK?) activity, such as rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease). Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting IKK2 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: December 28, 2010
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey K. Kerns, Michael Lindenmuth, Xichen Lin, Hong Nie, Sonia M. Thomas
  • Patent number: 7788756
    Abstract: A brush part for an electric toothbrush in which tufts of bristles are arranged in polygons, and in which the tufts of bristles lean, either around the polygons or inwardly and outwardly, so that the tuft alignments converge and preferably cross.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: September 7, 2010
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventor: Hans Kraemer
  • Patent number: 7757333
    Abstract: A toothbrush head comprising a mid section, a tip section resiliently flexibly connected to the tip end of the mid section, and at least two side sections each resiliently flexibly connected to the mid- or tip- section at respective points on widthways opposite sides of the mid- or tip- section.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: July 20, 2010
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventor: Massimo Battaglia
  • Patent number: 7744360
    Abstract: A process for making a toothbrush head comprising widthways adjacent sections, the process comprising the stages of first making the head in an injection moulding process with the sections relatively spaced apart from each other in a widthways direction, then secondly moving the sections of the so formed head relatively spaced closer to each other in a widthways direction. An apparatus for performing the process is also disclosed.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: June 29, 2010
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co., KG
    Inventors: Winfried Ebner, Hans Kraemer, Berthold Meyer, Andreas Walgenbach
  • Patent number: 7725972
    Abstract: A head for an electric toothbrush having first and second brush parts, one of which is rotary and the other is reciprocally moveable or static. Preferred forms have elastomeric oral hygiene parts, and electric toothbrush heads with novel ā€œVā€ sectioned oral hygiene parts are also disclosed.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: June 1, 2010
    Assignee: GlaxoSmithKLine Consumer GmbH & Co. KG
    Inventors: Tamas Berde, Christoph Geiberger, Ralph Francis Walker
  • Patent number: 7696728
    Abstract: A combination of an electrically powered toothbrush incorporating an electric power supply which comprises a capacitor, and a charging unit which incorporates one or more replaceable or rechargeable battery cells, enabling recharging of the capacitor without connection to the main electricity supply.
    Type: Grant
    Filed: November 2, 2004
    Date of Patent: April 13, 2010
    Assignee: Glaxo Group Limited
    Inventors: David Murray Cross, David Richard Stonehouse, Timothy Michael Wood
  • Patent number: 7691309
    Abstract: This invention relates to a process for making toothbrushes, in particular an injection moulding process.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: April 6, 2010
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventors: Winfried Ebner, Wolf-Dieter Mueller
  • Patent number: 7651988
    Abstract: A cleanser composition suitable for use with oral appliances, which provides a sensory signal to the user. The sensory signal is such that the user believes the signal to indicate that cleansing of the oral device if occurring or, alternatively, that cleansing action has ceased.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: January 26, 2010
    Assignee: SmithKline Beecham Corporation
    Inventors: Charles V. Dullea, Stanley J. Lech, Naresh I. Mehta, Stuart Wilensky
  • Patent number: 7549186
    Abstract: A toothbrush head comprising three widthways adjacent sections in which the tip end of the middle section is enlarged into a bristle-carrying tip pad, there is an intermediate bristle-carrying pad between the tip pad and the base end of the head, with narrow link regions between the pads and the intermediate pad and the handle. The sections are connected to the toothbrush handle by flexible necks. The bristle distribution of a multi-section toothbrush head is thereby optimized.
    Type: Grant
    Filed: November 5, 2003
    Date of Patent: June 23, 2009
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co.
    Inventor: Christoph Geiberger
  • Patent number: 7546658
    Abstract: A toothbrush head having elastomeric oral hygiene parts in the form of elastomeric strips aligned non-perpendicular to the length direction of the head. Preferably adjacent pairs of strips are linked to form a strip of ā€œVā€ cross section. Preferably the head comprises flexibly linked segments and is flexibly linked to the toothbrush handle.
    Type: Grant
    Filed: October 3, 2002
    Date of Patent: June 16, 2009
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventors: Michael Koeth, Wolf-Dieter Mueller, Klaus Reinbold, Thomas Clos, Andreas Lanvers, Christoph Geiberger
  • Patent number: 7526828
    Abstract: A toothbrush with a cleaning zone on which tooth-cleaning elements are arranged, which are pressed against the teeth during cleaning with a cleaning force, and with a deformable element by which the cleaning zone is can be adapted to the shape of the tooth surface by the cleaning force, where the deformable element has at least a first flexible wing facing towards the cleaning zone and a second such wing facing away from the cleaning zone, and also at least one guide element, and where the first and second wings are held together moveably by the guide element. In order to provide an improved toothbrush which cleans the teeth more effectively and at the same time more gently, it is provided according to the invention that the wings form a wedge, by being connected together at one end and distanced from each other at the other end.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: May 5, 2009
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co KG
    Inventor: Leif Kniese
  • Patent number: 7482458
    Abstract: NK3 receptor antagonists of formula (I): are useful in treating inter alia pulmonary disorders, CNS disorders and neurodegenerative disorders.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: January 27, 2009
    Assignee: SmithKline Beecham Farmaceutica S.p.A.
    Inventors: Carlo Farina, Giuseppe Arnaldo Maria Giardina, Mario Grugni, Luca Francesco Raveglia
  • Patent number: 7405301
    Abstract: This invention relates to a method for N-demethylating an N-methyl morphinane comprising the steps of: (i) treating said N-methyl morphinane with an oxidizing agent to form the N-oxide morphinane; and (ii) treating said N-oxide morphinane with a reducing agent. This invention also relates to a method for oxidizing a ?7-morphinane compound to a ?6, ?8-morphinane compound, comprising the steps of treating said ?7-morphinane with ?-MnO2 for a time and under conditions sufficient to oxidize said ?7-morphinane, and treating the ?-MnO2 with glycol or a derivative thereof, and/or an inorganic salt.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: July 29, 2008
    Assignee: GlaxoWellcome Australia Ltd.
    Inventors: Peter Scammells, Nicholas Gathergood, Justin Ripper
  • Cap
    Patent number: D573019
    Type: Grant
    Filed: September 26, 2006
    Date of Patent: July 15, 2008
    Assignee: Glaxo Group Limited
    Inventor: Gary Spencer
  • Patent number: D578768
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: October 21, 2008
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventor: Christoph Geiberger
  • Patent number: D582681
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: December 16, 2008
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventors: Christoph Geiberger, Klaus Reinbold
  • Patent number: D590597
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: April 21, 2009
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventor: Christoph Geiberger
  • Patent number: D623415
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: September 14, 2010
    Assignee: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG
    Inventor: Christoph Geiberger