Abstract: A distributed, reconfigurable statistical signal processing apparatus comprises an array of discrete-time analog signal processing circuitry for statistical signal processing based on a local message-passing algorithm and digital configuration circuitry for controlling the functional behavior of the array of analog circuitry. The input signal to the apparatus may be expressed as a probabilistic representation. The analog circuitry may comprise computational elements arranged in a network, with a receiving module that assigns probability values when an input signal arrives and communicates the probability values to one of the computational elements, the computational elements producing outputs based on the assigned probability values. The signal processing apparatus may be an analog logic automata cell or an array of cells, wherein each cell is able to communicate with all neighboring cells.

Abstract: A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide to the nucleic acid, determining whether the nucleotide or the oligonucleotide is added to the nucleic acid by detecting whether there is an increase in electrophoretic force applied to the solid support when an electric field and a magnetic field gradient are applied to the support, wherein the increase in electrophoretic force applied to the support is caused by adding the nucleotide or the oligonucleotide to the nucleic acid, repeating the addition reaction and determination steps if the nucleotide or the oligonucleotide is not added to the nucleic acid, and continuing until the immobilized nucleic acid has a desired sequence and length.

Abstract: A method for implementing a logic operation employs an all fluid-based no-moving part micro-mechanical logic family of microfluidic bubble logic devices that are constructed from complex sequences of microfluidic channels, microfluidic bubble modulators for programming the devices, and microfluidic droplet/bubble memory elements for chemical storage and retrieval. The input is a sequence of bubbles/droplets encoding information, with the output being another sequence of bubbles/droplets. For performing a set of reactions/tasks, the modulators program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the microfluidic channel sequence, utilizing the generated bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries.

Abstract: A self-replicating monolayer system employing polymerization of monomers or nanoparticle ensembles on a defined template provides a method for synthesis of two-dimensional single molecule polymers. Systems of self-replicating monolayers are used as templates for growth of inorganic colloids. A preferred embodiment employs SAM-based replication, wherein an initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition. The second monolayer is polymerized in place and the monolayers are separated to form a replicate. Both may then function as templates for monolayer assemblies. A generic self-replicating monomer unit comprises a polymerizable moiety attached by methylene repeats to a recognition element and an ending unit that will not interfere with the chosen recognition chemistry. The recognition element is self-complementary, unless a set of two replicating monomers with compatible cross-linking chemistry is employed.

Abstract: A conversation shielding system comprises sensors that detect the location of a confidential conversation and the presence and location of a potential eavesdropper, audio output devices that produce masking sounds to shield the conversation from the eavesdropper, and a controller that automatically controls the operation of the output devices in response to data from the sensors. An optional portable controller may manually engage the system. A method for shielding conversation comprises identifying a conversation to be shielded, detecting a potential eavesdropper, automatically determining masking sound types, locations and volume that will shield the conversation, directing emission of masking sounds from at least one audio output device in order to shield the conversation, including adjusting the masking sound type, location, and volume in response to movement of the conversation or the eavesdropper, and continuing to shield the conversation until it ends or the eavesdropper is no longer detected.

Abstract: In a method for synthesizing a long nucleic acid molecule, a first immobilized nucleic acid has a first 5? region and a first 3? region and a second immobilized nucleic acid has a second 5? region and a second 3? region. The second 3? region and the first 5? region have identical nucleic acid sequences. An oligonucleotide is hybridized to the first 3? region, extending the hybridized oligonucleotide and producing a first extension product having a 3? region that is complementary to the first 5? region. The 3? region of the first extension product is hybridized to the second 3? region, extending the 3? region of the first extension product and producing a synthesized nucleic acid molecule having a 3? region that is complementary to the second 5? region, wherein the synthesized nucleic acid molecule has a sequence complementary to the first and second 3? and 5? regions.

Abstract: A holographic video display comprises a monochromatic light source, a video signal generator, guided-wave acousto-optic modulators for diffracting light according to signals received from the video signal generator, a vertical scanning subsystem, and an optical path between the acousto-optic modulator and the vertical scanning subsystem. The optical path preferably comprises a Bravais lens system, first and second Fourier transform lens systems, and at least one holographic optical element or stationary mirror of continuous helical shape.

Abstract: A technique for forming nanostructures including a definition of a charge pattern on a substrate and introduction of charged molecular scale sized building blocks (MSSBBs) to a region proximate the charge pattern so that the MSSBBs adhere to the charge pattern to form the feature.

Abstract: A method and system provide routing of signals through a communications network. A transmitted signal is received. The signal has an associated parameter that is monitored as the signal is received. The parameter indicates the extent to which prior retransmission of the signal has occurred. The signal is retransmitted only if its parameter satisfies at least one predetermined criterion.

Abstract: A family of reconfigurable, charge-conserving asynchronous logic elements that interact with their nearest neighbors permits design and implementation of circuits that are asynchronous at the bit level, rather than at the level of functional blocks. These elements pass information by means of charge packets (tokens), rather than voltages. Each cell is self-timed, and cells that are configured as interconnect perform at propagation delay speeds, so no hardware non-local connections are needed. An asynchronous logic element comprises a set of edges for asynchronous communication with at least one neighboring cell, each edge having an input for receiving tokens from neighboring cells and an output for transferring an output charge packet to at least one neighboring cell, and circuitry configured to perform a logic operation utilizing received charge packets as inputs and to produce an output charge packet reflecting the result of the logic operation.

Abstract: A family of reconfigurable asynchronous logic elements that interact with their nearest neighbors permits reconfigurable implementation of circuits that are asynchronous at the bit level, rather than at the level of functional blocks. These elements pass information by means of tokens. Each cell is self-timed, and cells that are configured as interconnect perform at propagation delay speeds, so no hardware non-local connections are needed. A reconfigurable asynchronous logic element comprises a set of edges for communication with at least one neighboring cell, each edge having an input for receiving tokens from neighboring cells and an output for transferring tokens to at least one neighboring cell, circuitry configured to perform a logic operation utilizing received tokens as inputs and to produce an output token reflecting the result of the logic operation, and circuitry.

Abstract: An all-additive method for direct fabrication of nanometer-scale planar and multilayer structures comprises the steps of acquiring a transferable material with a submillimeter-scale tip, depositing at least a portion of the acquired first transferable material at a predetermined location onto a substrate without a bridging medium, and repeating to create a structure using the transferable material.

Abstract: A collaborative online tele-operation system allows an audience of many participants to simultaneously share control of a single remote actor, such that the actions of the actor are based on the ongoing collective preferences of the audience.

Abstract: This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors within nucleic acid molecules.

Abstract: Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries.

Abstract: Surface impacts are located and characterized based on an acoustic signal produced by the impact despite the presence of signal dispersion. Acoustic signals from the surface may be compared to acoustic signals detected external to the surface in order to eliminate spurious impact sensing due to external sounds. Low-frequency acoustic signals may be sensed and identified as explicit hard “bangs” which are of limited utility for pointing and tracking applications.

Abstract: This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors within nucleic acid molecules.

Abstract: A quasi-passive wake-up function for an electronic device that employs a continuous low power standby mode compares a received signal to a predetermined signal and wakes up the device when the received signal is the same as the predetermined signal. An electronic device having a quasi-passive wakeup function includes a receiver for receiving at least one stimulus signal, a comparator for comparing the received signal to a predetermined signal, and at least one logic gate for waking up the electronic device when the received stimulus signal is the predetermined signal. In one application, identification tags are used to distinguish a unique tagged item from among a plurality of items with a similar appearance. When an interrogation signal is not present, the tags sleep at a very low power level.

Abstract: Methods for applications such as signal processing, analysis, and coding/decoding replace digital signal processing elements with analog components are implemented by combining soft logic gates and filters, permitting the functionality of complex finite state machines to be implemented.

Abstract: A digital assembler for creating three-dimensional objects from digital materials made out of discrete components comprises an assembly head, error correction mechanism, parts feeder, and a controller. The assembly head comprises several blades, each with a different function, that move in a linear direction as a unit, assembling the object line-by-line. One blade adds digital materials, another performs error recognition, another performs error removal, and another fills in new digital material where previously removed. In a method for building a structure out of digital materials, a new line is fed to the assembly head and added to the structure. Simultaneously, the new line is pressed down, the last line is checked for errors, the line before last is removed if errors were found during the last cycle, and the line second before last is replaced if it was removed during the previous cycle.