Patents Represented by Attorney Norton S. Johnson
  • Patent number: 5372717
    Abstract: The present invention relates to the removal of metal ion contaminants as their anionic complexes from a variety of solutions containing said metal ion contaminants on an anion exchange resin, and the separation and purification of the anionic metal complexes by chromatographic elution utilizing a specially designed apparatus that enhances and maximizes the effects caused by different metal complex dissociation constants.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: December 13, 1994
    Assignee: PACT, Incorporated
    Inventors: Robert B. Abolt, Gerald D. Knepper
  • Patent number: 5246591
    Abstract: The present invention relates to the removal of metal ion contaminants as their anionic complexes from a variety of solutions containing said metal ion contaminants on an anion exchange resin, and the separation and purification of the anionic metal complexes by chromatographic elution utilizing a specially designed apparatus that enhances and maximizes the effects caused by different metal complex dissociation constants.
    Type: Grant
    Filed: July 6, 1992
    Date of Patent: September 21, 1993
    Assignee: PACT, Incorporated
    Inventors: Robert B. Abolt, Gerald D. Knepper
  • Patent number: 5040487
    Abstract: The present invention relates to a method of control of the Zebra Mussel from infestation of:(a) waterworks by applying an effective amount of ozone to a fresh (raw) water system of the waterworks,(b) cooling system of power plants and industrial plants by applying an effective amount of ozone to the intake water of the system, and(c) industrial process water systems by supplying an effective amount of ozone to the intake water of the system.
    Type: Grant
    Filed: May 3, 1990
    Date of Patent: August 20, 1991
    Assignee: Bollyky Associates, Inc.
    Inventors: L. Joseph Bollyky, Wilfred L. LePage
  • Patent number: 4360688
    Abstract: Novel compounds are disclosed of the classes: ##STR1## wherein the subscript n is an integer from 3-5, inclusive, R.sub.1 is hydrogen or R.sub.2 ; R.sub.2 and R.sub.3 consist essentially of C.sub.1 -C.sub.6 alkyl and R.sub.2 may be the same as or different from R.sub.3, and wherein Aryl consists essentially of phenyl and phenyl substituted with halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, and trifluoromethyl;(b) derivatives of furan having the formula ##STR2## wherein R.sub.4 consists essentially of hydrogen and C.sub.1 -C.sub.6 alkyl, and W is either carbonyl or carbinol; and(c) cyclopentenonyl compounds having the formulas ##STR3## wherein R.sub.5 consists essentially of hydrogen and C.sub.1 -C.sub.6 alkyl, P.sub.1 is hydrogen or a protective group, Y is either ##STR4## A new process is disclosed for preparing 1-(methyl)-16,16-(dimethyl)-11-alpha-15-alpha-dihydroxy-9-oxo-2,13,trans, trans-prostadienoate, and congeners thereof, including racemic mixtures.
    Type: Grant
    Filed: May 21, 1981
    Date of Patent: November 23, 1982
    Assignee: American Cyanamid Company
    Inventor: Middleton B. Floyd, Jr.
  • Patent number: 4358605
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16- substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion, and particularly, alkyl esters, such as the methyl ester, of such acids.
    Type: Grant
    Filed: May 8, 1980
    Date of Patent: November 9, 1982
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Martin J. Weiss, Charles V. Grudzinskas, Sow-Mei L. Chen
  • Patent number: 4291174
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation inhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 22, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4291026
    Abstract: This disclosure describes reversible complexes made from antibiotic trans-BM123.nu. and water soluble pamoate salts and a process for preparing same. These highly stable complexes are useful as animal feed supplements which significantly enhance the growth rate of animals and poultry.
    Type: Grant
    Filed: August 28, 1979
    Date of Patent: September 22, 1981
    Assignee: American Cyanamid Company
    Inventors: Martin Tobkes, Murray Dann, Irving Klothen, Larry D. Spicer, David R. Williams
  • Patent number: 4291175
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 22, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4289910
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 15, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4288632
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4288630
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4288629
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation inhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4288633
    Abstract: Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: September 8, 1981
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Middleton B. Floyd, Jr.
  • Patent number: 4283550
    Abstract: This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.
    Type: Grant
    Filed: September 27, 1979
    Date of Patent: August 11, 1981
    Assignee: American Cyanamid
    Inventor: Middleton B. Floyd, Jr.
  • Patent number: 4281153
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.
    Type: Grant
    Filed: January 17, 1980
    Date of Patent: July 28, 1981
    Assignee: American Cyanamid
    Inventors: Middleton B. Floyd, Jr., Martin J. Weiss, Charles V. Grudzinskas, Sow-Mei Lai Chen
  • Patent number: 4278806
    Abstract: The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E and F series wherein C-16 is substituted with hydrogen, methyl, vinyl or ethynyl and C-19 substituted with chloro and the .beta.-chain consists of 7 carbon atoms.
    Type: Grant
    Filed: June 7, 1979
    Date of Patent: July 14, 1981
    Assignee: American Cyanamid Company
    Inventor: Allan Wissner
  • Patent number: 4258180
    Abstract: C6-Modified cyclodextrin sulfate salts useful as complement inhibitors.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: March 24, 1981
    Assignee: American Cyanamid Company
    Inventors: Arthur J. Lewis, Seymour Bernstein
  • Patent number: 4258034
    Abstract: Lactobionic acid poly(H-sulfate) and salts thereof, useful as complement inhibitors.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: March 24, 1981
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4247535
    Abstract: Modified cyclodextrin sulfate salts useful as complement inhibitors.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: January 27, 1981
    Assignee: American Cyanamid Company
    Inventors: Arthur J. Lewis, Seymour Bernstein
  • Patent number: 4247466
    Abstract: Compounds of lactone metabolites of 3-(4-Biphenylylcarbonyl)propionic acid useful as anti-inflammatory and anti-platelet aggregation agents.
    Type: Grant
    Filed: July 5, 1979
    Date of Patent: January 27, 1981
    Assignee: American Cyanamid Company
    Inventor: Fortunato S. Chiccarelli